Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products
Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …
Structural diversity, bioactivities, and biosynthesis of natural diterpenoid alkaloids
Y Shen, WJ Liang, YN Shi, EJ Kennelly… - Natural Product …, 2020 - pubs.rsc.org
Covering: 2009 to 2018. Diterpenoid alkaloids, originating from the amination of natural
tetracyclic diterpenes, are a diverse class of compounds having complex structural features …
tetracyclic diterpenes, are a diverse class of compounds having complex structural features …
The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation
M Zhang, H Fan, S Tan, Q Tang, X Liu, D Zuo… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Inflammatory bowel disease (IBD) is one of the most
common chronic inflammatory illnesses of the gastrointestinal tract due to the imbalance of …
common chronic inflammatory illnesses of the gastrointestinal tract due to the imbalance of …
[HTML][HTML] Phytochemical constituents, antioxidant activity, and toxicity assessment of the seed of Spondias mombin L.(Anacardiaceae)
OO Abiodun, ME Nnoruka, RO Tijani - Turkish Journal of …, 2020 - ncbi.nlm.nih.gov
Objectives: Increased generation of free radicals exceeding the antioxidant capacity of the
host is deleterious. Thus new, potent, and safe antioxidants will be a valuable addition to the …
host is deleterious. Thus new, potent, and safe antioxidants will be a valuable addition to the …
Two new C19-diterpenoid alkaloids from Aconitum smirnovii
B Zhao, N Ablajan, JY Zhao, DR Kodirova… - Phytochemistry …, 2020 - Elsevier
Two new C 19-diterpenoid alkaloids, smirnotine A (1) and smirnotine B (2), together with five
known diterpenoid alkaloids (3-7) were isolated from the aerial part of Aconitum smirnovii …
known diterpenoid alkaloids (3-7) were isolated from the aerial part of Aconitum smirnovii …
Phytochemicals and their role in pharmaceuticals
A Suresh, J Abraham - Advances in Pharmaceutical Biotechnology …, 2020 - Springer
Researchers and pharmacists are replacing synthetic chemicals with natural resources for
drug manufacturing purposes. Plants produce secondary metabolites which possess …
drug manufacturing purposes. Plants produce secondary metabolites which possess …
Beneficial effect of Bidens pilosa L. (Asteraceae) in a rat model of colitis
OO Abiodun, AS Sosanya, N Nwadike… - Journal of Basic and …, 2020 - degruyter.com
Background Bidens pilosa (BP) possessed anti-inflammatory, antioxidant, and
immunomodulatory activities. Its beneficial effects on intestinal inflammation and oxidative …
immunomodulatory activities. Its beneficial effects on intestinal inflammation and oxidative …
Diterpenoid alkaloids with chemotaxonomic significance from Aconitum spathulatum
Diterpenoid alkaloids have been acknowledged as of chemotaxonomic significance in
plants from the genus Aconitum (Ranunculaceae). Phytochemical investigation on the …
plants from the genus Aconitum (Ranunculaceae). Phytochemical investigation on the …
[PDF][PDF] Protective Effect of Trichilia monadelpha (TM) Thonn JJ de Wilde in Trinitrobenzene Sulfonic Acid Induced Colitis in Rats
O Abiodun, F Ogunleye… - ACTA Pharmaceutica …, 2020 - actapharmsci.com
Trichilia monadelpha (TM) is a plant commonly used to treat gastrointestinal disorders,
inflammatory diseases and pain. This study evaluated the effect of aqueousmethanol extract …
inflammatory diseases and pain. This study evaluated the effect of aqueousmethanol extract …