Alleviation of liver dysfunction, oxidative stress and inflammation underlies the protective effect of ferulic acid in methotrexate-induced hepatotoxicity

M Roghani, H Kalantari, MJ Khodayar… - Drug design …, 2020 - Taylor & Francis
Introduction In multiple studies, involvement of oxidative stress in the pathogenesis of
methotrexate (MTX)-mediated liver damage has been confirmed. Use of many drugs has …

Gallic acid and ferulic acid protect the liver from thioacetamide-induced fibrosis in rats via differential expression of miR-21, miR-30 and miR-200 and impact on TGF …

RM Hussein, MM Anwar, HS Farghaly… - Chemico-biological …, 2020 - Elsevier
This study evaluates the possible protective effects of gallic acid (GaA) and ferulic acid (FeA)
against an experimentally induced liver fibrosis by thioacetamide (TAA) in rats. Animals …

Metabolism study of hesperetin and hesperidin in rats by UHPLC-LTQ-Orbitrap MSn

Q Jiao, L Xu, L Jiang, Y Jiang, J Zhang, B Liu - Xenobiotica, 2020 - Taylor & Francis
Hesperidin (HPD) and hesperetin (HPT), as a kind of flavonone compounds, are abundant
in citrus fruits with various pharmacological effects. HPD and HPT are not always consistent …

Phytochemicals as antidepressants

Khushboo, A Kumar, B Sharma - Advances in Pharmaceutical …, 2020 - Springer
Depression characterized as a mental disorder occupies the fourth position in the list of
frequent global brain-related diseases. It is believed to occupy the second position in that list …

[PDF][PDF] Emerging mechanisms and potential antidepressant action of medicinal plants

J Gupta, R Gupta, KK Varshney - Int J Pharm Sci Res, 2020 - researchgate.net
Depression is a common heterogeneous, debilitating and lifethreatening mood disorder
affecting different segments of the community. Several chemical and synthetic medicines as …