Role of PI3K/AKT pathway in cancer: the framework of malignant behavior

N Jiang, Q Dai, X Su, J Fu, X Feng, J Peng - Molecular biology reports, 2020 - Springer
Given that the PI3K/AKT pathway has manifested its compelling influence on multiple
cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in …

Linear and circular PVT1 in hematological malignancies and immune response: two faces of the same coin

M Ghetti, I Vannini, CT Storlazzi, G Martinelli… - Molecular cancer, 2020 - Springer
Non coding RNAs (ncRNAs) have emerged as regulators of human carcinogenesis by
affecting the expression of key tumor suppressor genes and oncogenes. They are divided …

Long noncoding RNA DLEU2 predicts a poor prognosis and enhances malignant properties in laryngeal squamous cell carcinoma through the miR-30c-5p/PIK3CD …

X Li, F Xu, Q Meng, N Gong, Z Teng, R Xu, M Zhao… - Cell death & …, 2020 - nature.com
Long noncoding RNAs (lncRNAs) have been identified as potential prognostic tools and
therapeutic biomarkers for a variety of human cancers. However, the functional roles and …

Poly (ADP‑ribosylation) of HMGB1 facilitates its acetylation and promotes HMGB1 translocation‑associated chemotherapy‑induced autophagy in leukaemia cells

Y Li, J Xie, X Li, J Fang - Oncology Letters, 2020 - spandidos-publications.com
Acute lymphoblastic leukaemia (ALL) is one of the most common and curable types of
cancer in paediatric patients. However, chemotherapeutic resistance is a difficult but …

The role of microRNAs in acute lymphoblastic leukaemia: from biology to applications

BEG Tapeh, MR Alivand, S Solali - Cell biochemistry and …, 2020 - Wiley Online Library
MicroRNAs (miRNAs) that are characterized by small, noncoding RNA have an essential
role in the pathogenesis of human diseases, including cancer. Furthermore, miRNAs, as a …

MiR-29b-3p cooperates with miR-29c-3p to affect the malignant biological behaviors in T-cell acute lymphoblastic leukemia via TFAP2C/GPX1 axis

M Zhuang, Q Chaolumen, L Li, B Chen, Q Su… - Biochemical and …, 2020 - Elsevier
Mounting evidence has illustrated the tumor regulatory roles of microRNAs (miRNAs) in T-
cell acute lymphoblastic leukemia (T-ALL), a malignant carcinoma originated from T-cell …

[HTML][HTML] Acidic leucine-rich nuclear phosphoprotein-32A expression contributes to adverse outcome in acute myeloid leukemia

S Huang, Z Huang, C Ma, L Luo, YF Li… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) is a novel regulator
of histone H3 acetylation and promotes leukemogenesis in acute myeloid leukemia (AML) …

Expression and Activity of Dysregulated miRNAs in T-ALL Development and Progression.

V Tse, J Yee, CA Tirado - Journal of the Association of …, 2020 - search.ebscohost.com
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological disease caused
by genetic abnormalities that manifest during the development of T-cell precursors …

Expresión de miR-26b, miR-100 y uno de sus genes blanco en células de leucemia linfoblástica aguda.

LA Martinez Jimenez - 2020 - ri.uagro.mx
Introducción: Los microRNAs participan en la regulación de la expresión génica en
múltiples procesos celulares, incluida la leucemogénesis. miR-26b y miR-100 en leucemia …