Calcification in atherosclerotic plaque vulnerability: friend or foe?

X Shi, J Gao, Q Lv, H Cai, F Wang, R Ye… - Frontiers in physiology, 2020 - frontiersin.org
Calcification is a clinical marker of atherosclerosis. This review focuses on recent findings on
the association between calcification and plaque vulnerability. Calcified plaques have …

Inflammation and atherosclerosis: what is on the horizon?

N Ruparelia, R Choudhury - Heart, 2020 - heart.bmj.com
Atherosclerosis is a chronic inflammatory process and both the innate and adaptive immune
systems 1 play central roles in its initiation and subsequent progression. 2 Experimental …

Coronary 18F-Sodium Fluoride Uptake Predicts Outcomes in Patients With Coronary Artery Disease

J Kwiecinski, E Tzolos, PD Adamson, S Cadet… - Journal of the American …, 2020 - jacc.org
Background Reliable methods for predicting myocardial infarction in patients with
established coronary artery disease are lacking. Coronary 18F-sodium fluoride (18F-NaF) …

Noninvasive imaging to assess atherosclerotic plaque composition and disease activity: coronary and carotid applications

M Daghem, R Bing, ZA Fayad, MR Dweck - Cardiovascular Imaging, 2020 - jacc.org
Cardiovascular disease is one of the leading causes of mortality and morbidity worldwide.
Atherosclerosis imaging has traditionally focused on detection of obstructive luminal …

Coronary 18F-Fluoride Uptake and Progression of Coronary Artery Calcification

MK Doris, MN Meah, AJ Moss… - Circulation …, 2020 - Am Heart Assoc
Background Positron emission tomography (PET) using 18F-sodium fluoride (18F-fluoride)
to detect microcalcification may provide insight into disease activity in coronary …

Atherosclerosis imaging with 18F-sodium fluoride PET: state-of-the-art review

PF Høilund-Carlsen, M Sturek, A Alavi… - European Journal of …, 2020 - Springer
Purpose We examined the literature to elucidate the role of 18F-sodium fluoride (NaF)-PET
in atherosclerosis. Methods Following a systematic search of PubMed/MEDLINE, Embase …

Determinants of pericoronary adipose tissue attenuation on computed tomography angiography in coronary artery disease

T Sugiyama, Y Kanaji, M Hoshino… - Journal of the …, 2020 - Am Heart Assoc
Background Recent studies have reported the association between pericoronary
inflammation assessed by pericoronary adipose tissue attenuation (PCATA) on computed …

Nanomedicine approaches for advanced diagnosis and treatment of atherosclerosis and related ischemic diseases

B Hu, KO Boakye‐Yiadom, W Yu… - Advanced …, 2020 - Wiley Online Library
Cardiovascular diseases (CVDs) remain one of the major causes of mortality worldwide. In
response to this and other worldwide health epidemics, nanomedicine has emerged as a …

18F-Sodium Fluoride (18F-NaF) for Imaging Microcalcification Activity in the Cardiovascular System

E Tzolos, MR Dweck - Arteriosclerosis, Thrombosis, and Vascular …, 2020 - Am Heart Assoc
Accumulating preclinical and clinical evidence suggests that calcification is one of the body's
primary responses to injury and a key pathological feature of cardiovascular disease …

Contemporary rationale for non-invasive imaging of adverse coronary plaque features to identify the vulnerable patient: a Position Paper from the European Society of …

MR Dweck, P Maurovich-Horvat, T Leiner… - European Heart …, 2020 - academic.oup.com
Atherosclerotic plaques prone to rupture may cause acute myocardial infarction (MI) but can
also heal without causing an event. Certain common histopathological features, including …