Gonadal sex differentiation: Supporting versus steroidogenic cell lineage specification in mammals and birds

MA Estermann, AT Major, CA Smith - Frontiers in cell and …, 2020 - frontiersin.org
The gonads of vertebrate embryos are unique among organs because they have a
developmental choice; ovary or testis formation. Given the importance of proper gonad …

Insights into gonadal sex differentiation provided by single-cell transcriptomics in the chicken embryo

MA Estermann, S Williams, CE Hirst, ZY Roly… - Cell reports, 2020 - cell.com
Although the genetic triggers for gonadal sex differentiation vary across species, the cell
biology of gonadal development was long thought to be largely conserved. Here, we present …

Developmental gene expression differences between humans and mammalian models

M Cardoso-Moreira, I Sarropoulos, B Velten, M Mort… - Cell reports, 2020 - cell.com
Identifying the molecular programs underlying human organ development and how they
differ from model species is key for understanding human health and disease …

Oestrogen in the chick embryo can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex that can support oogenesis

S Guioli, D Zhao, S Nandi, M Clinton… - …, 2020 - journals.biologists.com
In chickens, the embryonic ovary differentiates into two distinct domains before meiosis: a
steroidogenic core (the female medulla), overlain by the germ cell niche (the cortex). The …

A phylogenetic comparative analysis on the evolution of sequential hermaphroditism in seabreams (Teleostei: Sparidae)

S Pla, C Benvenuto, I Capellini, F Piferrer - Scientific reports, 2020 - nature.com
The Sparids are an ideal group of fishes in which to study the evolution of sexual systems
since they exhibit a great sexual diversity, from gonochorism (separate sexes) to …

Why isn't sex optional? Stem-cell competition, loss of regenerative capacity, and cancer in metazoan evolution

C Fields, M Levin - Communicative & Integrative Biology, 2020 - Taylor & Francis
Animals that can reproduce vegetatively by fission or budding and also sexually via
specialized gametes are found in all five primary animal lineages (Bilateria, Cnidaria …

A suggested bisphenol A metabolite (MBP) interfered with reproductive organ development in the chicken embryo while a human-relevant mixture of phthalate …

A Mentor, CG Bornehag, M Jönsson… - Journal of Toxicology …, 2020 - Taylor & Francis
Bisphenol A (BPA) and phthalate diesters are ubiquitous environmental contaminants. While
these compounds have been reported as reproductive toxicants, their effects may partially …

Germline complementation in sheep

Z McLean - 2020 - researchspace.auckland.ac.nz
Controlling the male germline through natural mating and artificial insemination drives
genetic improvement in sheep and cattle, respectively. Multiplication of the best male …

Cystic proliferation of embryonic germ stem cells is necessary to reproductive success and normal mating behavior in medaka

LF Arias Padilla, DC Castañeda-Cortés, IF Rosa… - bioRxiv, 2020 - biorxiv.org
The production of an adequate number of gametes in both sexes is necessary for normal
reproduction, for which the regulation of proliferation from early gonadal development to …

Inter-organ control of gut sexual dimorphism by steroid hormone signaling in Drosophila

SMH Ahmed - 2020 - archiv.ub.uni-heidelberg.de
Suggestive evidence points that exogenous exposure to steroid hormones has detrimental
consequences that are not well explored specifically in the gut, where nutrient uptake …