Cancer-derived extracellular vesicles (EVs) are regarded as having promising potential to
be used as therapeutics and disease biomarkers. Mechanistically, EVs have been shown to …

Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …

Extracellular vesicles act as shuttle vectors or signal transducers that can deliver specific
biological information and have progressively emerged as key regulators of organized …

The lung is the organ with the highest vascular density in the human body. It is therefore
perceivable that the endothelium of the lung contributes significantly to the circulation of …

Tumors strongly depend on their surrounding tumor microenvironment (TME) for growth and
progression, since stromal elements are required to generate the optimal conditions for …

Therapeutic failure in prostate cancer (PC) is believed to result from its unusually invasive
and metastatic nature. Cancer-associated fibroblasts (CAFs) are essential in the tumor …

Angiogenesis is a multistep process and various molecules are involved in regulating it.
Extracellular vesicles are cell-derived particles, secreted from several types of cells and are …

Prostate cancer (PCa) is the second most common cause of cancer-related mortality among
men in the developed world. Conventional anti-PCa therapies are not effective for patients …

Several reports have demonstrated that Epstein-Barr virus (EBV) encoded latent membrane
protein 1 (LMP1), which is transferred by extracellular vesicles (EVs) or exosomes, can …

Homotypic and heterotypic interactions between cells are of crucial importance in
multicellular organisms for the maintenance of physiological functions. Accordingly, changes …