Chronic kidney disease as oxidative stress-and inflammatory-mediated cardiovascular disease

A Podkowińska, D Formanowicz - Antioxidants, 2020 - mdpi.com
Generating reactive oxygen species (ROS) is necessary for both physiology and pathology.
An imbalance between endogenous oxidants and antioxidants causes oxidative stress …

Research advances in the mechanisms of hyperuricemia‐induced renal injury

H Su, C Yang, D Liang, H Liu - BioMed Research International, 2020 - Wiley Online Library
Uric acid is the end product of purine metabolism in humans, and its excessive accumulation
leads to hyperuricemia and urate crystal deposition in tissues including joints and kidneys …

Mechanisms of cardiovascular disorders in patients with chronic kidney disease: a process related to accelerated senescence

J Carracedo, M Alique, C Vida, G Bodega… - Frontiers in cell and …, 2020 - frontiersin.org
Cardiovascular diseases (CVDs), especially those involving a systemic inflammatory
process such as atherosclerosis, remain the leading cause of morbidity and mortality in …

Probiotics, prebiotics and synbiotics—a promising strategy in prevention and treatment of cardiovascular diseases?

B Olas - International journal of molecular sciences, 2020 - mdpi.com
Recent evidence suggests that probiotics, prebiotics and synbiotics may serve as important
dietary components in the prevention (especially) and treatment of cardiovascular diseases …

Unfavorable effects of peritoneal dialysis solutions on the peritoneal membrane: the role of oxidative stress

S Roumeliotis, E Dounousi, M Salmas, T Eleftheriadis… - Biomolecules, 2020 - mdpi.com
One of the main limitations to successful long-term use of peritoneal dialysis (PD) as a renal
replacement therapy is the harmful effects of PD solutions to the structure and function of the …

Vascular calcification in chronic kidney disease: the role of vitamin K-dependent matrix Gla protein

S Roumeliotis, E Dounousi, M Salmas… - Frontiers in …, 2020 - frontiersin.org
Arterial calcification is highly prevalent in chronic kidney disease (CKD) patients and is
associated with cardiovascular (CV) morbidity and mortality. Patients at early CKD stages …

High-protein diet induces hyperuricemia in a new animal model for studying human gout

F Hong, A Zheng, P Xu, J Wang, T Xue, S Dai… - International Journal of …, 2020 - mdpi.com
Hyperuricemia is a central risk factor for gout and increases the risk for other chronic
diseases, including cardiometabolic disease, kidney disease, and hypertension …

Anti-hyperuricemic potential of stevia (Stevia rebaudiana Bertoni) residue extract in hyperuricemic mice

A Mehmood, L Zhao, M Ishaq, W Xin, L Zhao… - Food & Function, 2020 - pubs.rsc.org
Hyperuricemia (HUA) is considered a potent risk factor for the development of gout, renal
failure, and cardiovascular disease. The current project was designed to use stevia (Stevia …

Mechanistic insights into hyperuricemia-associated renal abnormalities with special emphasis on epithelial-to-mesenchymal transition: pathologic implications and …

P Balakumar, A Alqahtani, NA Khan… - Pharmacological …, 2020 - Elsevier
Though the pathogenesis of hyperuricemia-induced renal complications is not precisely
known, hyperuricemia has been recognized as an independent risk factor for renal disease …

[HTML][HTML] Renoprotective effect of stevia residue extract on adenine-induced chronic kidney disease in mice

A Mehmood, L Zhao, M Ishaq, OD Zad, L Zhao… - Journal of functional …, 2020 - Elsevier
The present study was performed to explore the renoprotective potential of a stevia residue
extract (STRE) on a mouse model of adenine-induced chronic kidney disease (CKD). The …