Nonrandomized real‐world evidence to support regulatory decision making: process for a randomized trial replication project
JM Franklin, A Pawar, D Martin… - Clinical …, 2020 - Wiley Online Library
Recent legislation mandates that the US Food and Drug Administration issue guidance
regarding when real‐world evidence (RWE) could be used to support regulatory decision …
regarding when real‐world evidence (RWE) could be used to support regulatory decision …
Risk for serious infection with low-dose glucocorticoids in patients with rheumatoid arthritis: a cohort study
MD George, JF Baker, K Winthrop, JY Hsu… - Annals of internal …, 2020 - acpjournals.org
Background: Low-dose glucocorticoids are frequently used for the management of
rheumatoid arthritis (RA) and other chronic conditions, but the safety of long-term use …
rheumatoid arthritis (RA) and other chronic conditions, but the safety of long-term use …
Comparing the 5-year diabetes outcomes of sleeve gastrectomy and gastric bypass: the National Patient-Centered Clinical Research Network (PCORNet) Bariatric …
KM McTigue, R Wellman, E Nauman, J Anau… - JAMA …, 2020 - jamanetwork.com
Importance Bariatric surgery can lead to substantial improvements in type 2 diabetes
(T2DM), but outcomes vary across procedures and populations. It is unclear which bariatric …
(T2DM), but outcomes vary across procedures and populations. It is unclear which bariatric …
Association of gabapentinoids with the risk of opioid-related adverse events in surgical patients in the United States
Importance The use of gabapentinoids in multimodal postoperative analgesia is increasing;
however, when coadministered with opioids, these drugs may potentiate central nervous …
however, when coadministered with opioids, these drugs may potentiate central nervous …
Sleep, suicide behaviors, and the protective role of sleep medicine
Abstract Objective/Background Sleep disturbance is associated with suicidal thoughts and
behaviors. The relationship of specific sleep disorders to suicide attempts is less well …
behaviors. The relationship of specific sleep disorders to suicide attempts is less well …
Outcomes of primary care delivery by nurse practitioners: Utilization, cost, and quality of care
CF Liu, PL Hebert, JH Douglas, EL Neely… - Health services …, 2020 - Wiley Online Library
Objective To examine whether nurse practitioner (NP)‐assigned patients exhibited
differences in utilization, costs, and clinical outcomes compared to medical doctor (MD) …
differences in utilization, costs, and clinical outcomes compared to medical doctor (MD) …
[HTML][HTML] Identifying goals of care
As a person ages or faces serious illness, decisions about medical care become more
challenging. When cure of a disease is not possible, treatments become focused on other …
challenging. When cure of a disease is not possible, treatments become focused on other …
Estimates of overall survival in patients with cancer receiving different treatment regimens: emulating hypothetical target trials in the Surveillance, Epidemiology, and …
LC Petito, X García-Albéniz, RW Logan… - JAMA network …, 2020 - jamanetwork.com
Importance The Surveillance, Epidemiology, and End Results (SEER)–Medicare linked
database may provide insights into the comparative effectiveness of oncological treatments …
database may provide insights into the comparative effectiveness of oncological treatments …
Association of fluoroquinolones with the risk of aortic aneurysm or aortic dissection
Importance Previous observational studies have suggested that fluoroquinolones are
associated with aortic aneurysm or dissection, but these studies may be subject to …
associated with aortic aneurysm or dissection, but these studies may be subject to …
Stress hyperglycemia and mortality in subjects with diabetes and sepsis
A Fabbri, G Marchesini, B Benazzi, A Morelli… - Critical care …, 2020 - journals.lww.com
Objectives: Poor glycemic control is associated with mortality in critical patients with
diabetes. The aim of the study was to assess the predicting value of stress hyperglycemia in …
diabetes. The aim of the study was to assess the predicting value of stress hyperglycemia in …