Leishmania infection triggers hepcidin‐mediated proteasomal degradation of Nramp1 to increase phagolysosomal iron availability

S Banerjee, R Datta - Cellular microbiology, 2020 - Wiley Online Library
Natural resistance–associated macrophage protein 1 (Nramp1) was originally discovered as
a genetic determinant of resistance against multiple intracellular pathogens, including …

[HTML][HTML] Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is …

MD Lewis, A Paun, A Romano, H Langston… - PLoS …, 2020 - journals.plos.org
Leishmania donovani causes visceral leishmaniasis (VL), which is typically fatal without
treatment. There is substantial variation between individuals in rates of disease progression …

Early high avidity specific IgG production in experimental hamster visceral leishmaniasis

CA de Carvalho, TF Ferrão, FS Cavalcante… - Parasitology …, 2020 - Springer
Visceral leishmaniasis (VL) by Leishmania (Leishmania) infantum is epidemic in Brazil.
Hypergammaglobulinemia appears early in patients with VL and is ineffective. Usually, high …

SLC11A1 (rs3731865) polymorphism and susceptibility to visceral leishmaniasis in HIV-coinfected patients from Northeastern Brazil

WL Barbosa Júnior, AM Justo, AMA Dos Santos… - Parasitology …, 2020 - Springer
Following the emergence of human immunodeficiency virus (HIV)/acquired
immunodeficiency syndrome (AIDS), the number of visceral leishmaniasis-HIV (VL-HIV) …

In vivo infection with Leishmania amazonensis to evaluate parasite virulence in mice

JI Aoki, A Hong, RA Zampieri, LM Floeter-Winter… - JoVE (Journal of …, 2020 - jove.com
Leishmania spp. are protozoan parasites that cause leishmaniases, diseases that present a
wide spectrum of clinical manifestations from cutaneous to visceral lesions. Currently, 12 …

Exposure factors associated with visceral leishmaniasis (kala-azar) in Loima Sub-County of Turkana County, Kenya

JA Lotukoi - 2020 - ir.jkuat.ac.ke
Visceral Leishmaniasis (Kala-azar) is a life-threatening vector borne disease caused by the
obligate intra-macrophage protozoan parasites known as Leishmania donovani and L …

A genome-wide association study highlights a regulatory role for IFNG-AS1 contributing to cutaneous leishmaniasis in Brazil

LC Castellucci, L Almeida, S Cherlin, M Fakiola… - bioRxiv, 2020 - biorxiv.org
Background Cutaneous leishmaniasis (CL) caused by Leishmania braziliensis remains an
important public health problem in Brazil. The goal of this study was to identify genetic risk …

Vaccines Against Leishmania Infection

MG Finn, AF Marques - US Patent App. 16/639,300, 2020 - Google Patents
US20200261558A1 - Vaccines Against Leishmania Infection - Google Patents
US20200261558A1 - Vaccines Against Leishmania Infection - Google Patents Vaccines …