The current guideline represents the 6th edition of the “Japanese Clinical Practice Guideline
for Diabetes” which has been revised every three years since its first appearance in 2004 to …

Cardiovascular mortality is a major cause of death among in type 2 diabetes (T2DM).
Endothelial dysfunction (ED) is a well-known important risk factor for the development of …

Given the intersection between diabetes mellitus and cardiovascular disease (CVD),
pharmacologic agents used to treat type 2 diabetes mellitus must show cardiovascular …

People with diabetes mellitus are at higher risk of ischaemic stroke and worse outcomes
thereafter. However, whether it is better to prescribe intensive glucose‐lowering treatment …

Metformin is the most commonly used glucose-lowering therapy (GLT) worldwide and
remains the first-line therapy for newly diagnosed individuals with type 2 diabetes (T2D) in …

Metformin along with other antidiabetic medications provide benefit to patients in the
treatment of type 2 diabetes mellitus, but caution is advised in certain scenarios to avoid …

Abstract Purpose of Review Among patients with type 2 diabetes (T2D), cardiovascular
disease (CVD) is the leading cause of death regardless of ethnicity. However, recent studies …

Objectives Hyperglycemia is associated with an increased risk of adverse cardiovascular
outcomes, such as heart failure, coronary heart disease, stroke, and in‐hospital mortality …

ポリファーマシーとは, ポリ (poly) とファーマシー (pharmacy) を組み合わせた造語であり,
複数の薬剤を同時使用することを含意する用語として国際的に用いられている …