Correlation and association analyses in microbiome study integrating multiomics in health and disease

Y Xia - Progress in molecular biology and translational …, 2020 - Elsevier
Correlation and association analyses are one of the most widely used statistical methods in
research fields, including microbiome and integrative multiomics studies. Correlation and …

A microbial sea of possibilities: current knowledge and prospects for an improved understanding of the fish microbiome

TPRA Legrand, JW Wynne, LS Weyrich… - Reviews in …, 2020 - Wiley Online Library
The mucosal surfaces of fish represent an important barrier that supports and regulates a
diverse array of microbial assemblages and contributes to the overall health and fitness of …

PICRUSt2 for prediction of metagenome functions

GM Douglas, VJ Maffei, JR Zaneveld, SN Yurgel… - Nature …, 2020 - nature.com
To the Editor—One limitation of microbial community marker-gene sequencing is that it does
not provide information about the functional composition of sampled communities …

[HTML][HTML] Tax4Fun2: prediction of habitat-specific functional profiles and functional redundancy based on 16S rRNA gene sequences

F Wemheuer, JA Taylor, R Daniel, E Johnston… - Environmental …, 2020 - Springer
Abstract Background Sequencing of 16S rRNA genes has become a powerful technique to
study microbial communities and their responses towards changing environmental …

[HTML][HTML] Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease

FJ Ryan, AM Ahern, RS Fitzgerald… - Nature …, 2020 - nature.com
Studies of inflammatory bowel disease (IBD) have been inconclusive in relating microbiota
with distribution of inflammation. We report microbiota, host transcriptomics, epigenomics …

[HTML][HTML] PROVIT: Supplementary probiotic treatment and vitamin B7 in depression—A randomized controlled trial

EZ Reininghaus, M Platzer, A Kohlhammer-Dohr… - Nutrients, 2020 - mdpi.com
Gut microbiota are suspected to affect brain functions and behavior as well as lowering
inflammation status. Therefore, an effect on depression has already been suggested by …

[HTML][HTML] Gut microbiome profiles are associated with type 2 diabetes in urban Africans

AP Doumatey, A Adeyemo, J Zhou, L Lei… - Frontiers in cellular …, 2020 - frontiersin.org
Gut dysbiosis has been associated with several disease outcomes including diabetes in
human populations. Currently, there are no studies of the gut microbiome composition in …

[HTML][HTML] Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine

SR Bogatyrev, JC Rolando, RF Ismagilov - Microbiome, 2020 - Springer
Background The upper gastrointestinal tract plays a prominent role in human physiology as
the primary site for enzymatic digestion and nutrient absorption, immune sampling, and drug …

[HTML][HTML] Lactobacillus acidophilus and L. plantarum improve health status, modulate gut microbiota and innate immune response of marron (Cherax cainii)

MJ Foysal, R Fotedar, MAB Siddik, A Tay - Scientific reports, 2020 - nature.com
This study aimed to investigate the combined effects of two most potent probiotic bacteria
Lactobacillus acidophilus and Lactobacillus plantarum on overall health and immune status …

Structured exercise alters the gut microbiota in humans with overweight and obesity—A randomized controlled trial

T Kern, MB Blond, TH Hansen, M Rosenkilde… - International journal of …, 2020 - nature.com
Objectives Studies suggest that exercise affects the composition and function of the human
gut microbiota, yet this has not been investigated in a randomized controlled trial. The …