The impact of antimicrobial stewardship program implementation at four tertiary private hospitals: results of a five-years pre-post analysis

A Al-Omari, A Al Mutair, S Alhumaid, S Salih… - … Resistance & Infection …, 2020 - Springer
Background Antimicrobial stewardship (AMS) programs have shown to reduce the
emergence of antimicrobial resistance (AMR) and health-care-associated infections (HAIs) …

Association Between Antibiotic Use and Hospital-onset Clostridioides difficile Infection in US Acute Care Hospitals, 2006–2012: An Ecologic Analysis

SV Kazakova, J Baggs, LC McDonald… - Clinical Infectious …, 2020 - academic.oup.com
Background Unnecessary antibiotic use (AU) contributes to increased rates of Clostridioides
difficile infection (CDI). The impact of antibiotic restriction on hospital-onset CDI (HO-CDI) …

Reducing fluoroquinolone use and Clostridioides difficile infections in community nursing homes through hospital–nursing home collaboration

CB Felsen, ESD Ashley, GR Barney, DL Nelson… - Journal of the American …, 2020 - Elsevier
Abstract Objective Nursing homes (NHs) are an important target for antibiotic stewardship
(AS). We describe a collaborative model to reduce Clostridioides difficile infections (CDIs) in …

Evaluation of a successful fluoroquinolone restriction intervention among high-risk patients: a mixed-methods study

J Tischendorf, M Brunner, MJ Knobloch, L Schulz… - PLoS …, 2020 - journals.plos.org
Objective We conducted a quality improvement initiative to restrict fluoroquinolone
prescribing on two inpatient units housing high-risk patients and applied a human factors …

Prescriber perceptions of fluoroquinolones, extended-spectrum cephalosporins, and Clostridioides difficile infection

JE Szymczak, BM Muller, NS Shakamuri… - Infection Control & …, 2020 - cambridge.org
Background: Fluoroquinolones (FQs) and extended-spectrum cephalosporins (ESCs) are
associated with higher risk of Clostridioides difficile infection (CDI). Decreasing the …

Untreated HWWs emerged as hotpots for ARGs

O Kayali, B Icgen - Bulletin of environmental contamination and toxicology, 2020 - Springer
Hospital wastewaters (HWWs) are reported to be hotspots for antibiotics and antibiotic-
resistant bacteria. However, limited information involves the impact of these effluents on …

Bundling probiotics with antimicrobial stewardship programs for the prevention of Clostridiodes difficile infections in acute care hospitals

R Kullar, S Johnson, LV McFarland… - Infectious Diseases in …, 2020 - journals.lww.com
Objective Several recommendations based on probiotics with a Clostridiodes difficile
infection (CDI) prevention bundle were developed. Methods Using a modified Delphi …

Oxygen and Metabolism: Digesting Determinants of Antibiotic Susceptibility in the Gut

LR Heinzinger, A Johnson, JI Wurster, R Nilson… - Iscience, 2020 - cell.com
Microbial metabolism is a major determinant of antibiotic susceptibility. Environmental
conditions that modify metabolism, notably oxygen availability and redox potential, can …

[HTML][HTML] Diarrea asociada a Clostridioides difficile en pacientes de servicios quirúrgicos en México

R Morfín-Otero, S Petersen-Morfín… - … de Gastroenterología de …, 2020 - Elsevier
Introducción Clostridioides difficile (CD) es la primera causa de diarrea asociada al cuidado
de salud en los países desarrollados. En los últimos años, la incidencia de la infección …

[HTML][HTML] Impact of dedicated infectious disease teamwork on the treatment and prognosis of patients with diabetic foot infection

X Li, X Qi, S Tian, R He, S Jiang, H Li - International Journal of Infectious …, 2020 - Elsevier
Objective The aim was to develop and evaluate the impact of a new model in which the
infectious disease (ID) physician and pharmacist work together to treat diabetic foot …