Bone remodeling is tightly regulated by a cross-talk between bone-forming osteoblasts and
bone-resorbing osteoclasts. Osteoblasts and osteoclasts communicate with each other to …

Self-maintaining resident macrophages populate all mammalian organs. In addition to their
role as immune sentinels, macrophages perform day-to-day functions essential to tissue …

Bone is an extremely dynamic tissue, undergoing continuous remodeling for its whole
lifetime, but its regeneration or augmentation due to bone loss or defects are not always …

Bone remodeling is essential for the repair and replacement of damaged and old bone. The
major principle underlying this process is that osteoclast-mediated resorption of a quantum …

Several virtual screening models are proposed to screen small molecules only targeting
primary miRNAs without selectivity. Few attempts have been made to develop virtual …

The balance between bone forming cells (osteoblasts/osteocytes) and bone resorbing cells
(osteoclasts) plays a crucial role in tissue homeostasis and bone repair. Several hormones …

Bone metabolic disorders include osteolysis, osteoporosis, osteoarthritis and rheumatoid
arthritis. Osteoblasts and osteoclasts are two major types of cells in bone constituting …

Octacalcium phosphate (OCP) is a material that can be converted to hydroxyapatite (HA)
under physiological environments and is considered a mineral precursor to bone apatite …

Air pollution is the second most important risk factor associated with noncommunicable
diseases after smoking. The effects of pollution on health are commonly attributable to …

Communication between osteoblasts and osteoclasts plays a key role in bone metabolism.
We describe here an unexpected role for matrix vesicles (MVs), which bud from bone …