The central dogma of molecular biology, developed from the study of simple organisms such
as Escherichia coli, has up until recently been that RNA functions mainly as an information …

Metabolic reprogramming is a hallmark of cancer. Mammalian genome is characterized by
pervasive transcription, generating abundant non-coding RNAs (ncRNAs). Long non-coding …

Background & Aims Estimates of absolute risk of colorectal cancer (CRC) are needed to
facilitate communication and better inform the public about the potentials and limits of cancer …

Abstract The N6-methyladenosine (m6A) modification plays important regulatory roles in
gene expression, cancer occurrence and metastasis. Herein, we aimed to explore the …

Genome-wide association studies (GWAS) have identified thousands of germline
susceptibility loci associated with risk for cancer as well as a wide range of other traits and …

We identified a novel long noncoding RNA (lncRNA) upregulated in colorectal cancer
(CRC). We elucidated its role and clinical significance in CRC carcinogenesis. Methods …

Background & Aims Polygenic risk scores (PRSs) could help to define starting ages for
colorectal cancer (CRC) screening. However, the role of PRS in determining the length of …

Background Increasing evidence suggests that conventional adenomas (CAs) and serrated
polyps (SPs) represent two distinct groups of precursor lesions for colorectal cancer (CRC) …

Purpose The effects of seaweed compounds have been studied in relation to colorectal
cancer (CRC) based on their ability to modulate carcinogen metabolism in vivo and in vitro …

FAM84B is a risk gene in breast and prostate cancers. Its upregulation is associated with
poor prognosis of prostate cancer, breast cancer, and esophageal squamous cell …