The Hippo pathway plays important roles in organ development, tissue regeneration, and
human diseases, such as cancer. In the canonical Hippo pathway, the MST1/2-LATS1/2 …

Mechanical cues from the cellular microenvironment are converted into biochemical signals
controlling diverse cell behaviours, including growth and differentiation. But it is still unclear …

CFL2, a skeletal muscle-specific member of the actin depolymerizing factor/cofilin protein
family, is known to be involved in the regulation of actin filament dynamics. Although the …

Skeletal myogenesis is a multi-stage process that includes the cell cycle exit, myogenic
transcriptional activation, and morphological changes to form multinucleated myofibers …

While many tissues fold in vivo in a highly reproducible and robust way, epithelial folds
remain difficult to reproduce in vitro, so that the effects and underlying mechanisms of local …

The development of epithelial lumens in ducts is essential to the functioning of various
organs and in organogenesis. Ductal elongation requires the collective migration of cell …

Mechanical cues from the cellular microenvironment are converted into biochemical signals
controlling diverse cell behaviours, including growth and differentiation. But it is still unclear …

Identification of pharmacological candidates for enhancing muscle endogenous repair has
been limited due to a lack of suitable in vitro models. To address this issue, our team …

Identification of pharmacological candidates for enhancing muscle endogenous repair has
been limited due to a lack of suitable in vitro models. To address this issue, our team …