Biodegradable Mg‐based metals may be promising orthopedic implants for treating
challenging bone diseases, attributed to their desirable mechanical and osteopromotive …

Colony-stimulating factor 1 receptor (CSF1R, also known as c-FMS) is a receptor tyrosine
kinase. Macrophage colony-stimulating factor (M-CSF) and IL-34 are ligands of CSF1R …

Bones as an alive organ consist of about 70% mineral and 30% organic component. About
200 million people are suffering from osteopenia and osteoporosis around the world. There …

The emerging concept of microbiota contributing to local mucosal homeostasis has fueled
investigation into its specific role in immunology. Gut microbiota is mostly responsible for …

Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/
macrophage–lineage cells into the bone–resorbing cells called osteoclasts. Because …

Biomaterials as bone substitutes are always considered as foreign bodies that can trigger
host immune responses. Traditional designing principles have been always aimed at …

Bone homeostasis is securely controlled by the dynamic well‐balanced actions among
osteoclasts, osteoblasts and osteocytes. Osteoclasts are large multinucleated cells that …

Offering up-to-date, comprehensive coverage of disease progression, diagnosis,
management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference …

Mesoporous bioactive glass nanoparticles (MBGNs) are emerging biomaterials for bone
repair/regeneration, considering their favorable pro-osteogenic and proangiogenic activities …

The host immune response is critical for in situ osteogenesis, but correlations between local
inflammatory reactions and biomaterial osteoinduction are still poorly understood. This study …