Biology of the human blood-nerve barrier in health and disease

EE Ubogu - Experimental neurology, 2020 - Elsevier
A highly regulated endoneurial microenvironment is required for normal axonal function in
peripheral nerves and nerve roots, which structurally consist of an outer collagenous …

[HTML][HTML] Studying the neuropsychological sequelae of SARS-CoV-2: lessons learned from 35 years of neuroHIV research

A Levine, N Sacktor, JT Becker - Journal of neurovirology, 2020 - Springer
The virology of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and the
human immune response to the virus are under vigorous investigation. There are now …

The Neurocognitive Assessment in the Metabolic and Aging Cohort (NAMACO) study: baseline participant profile

M Metral, KEA Darling, I Locatelli, I Nadin… - HIV …, 2020 - Wiley Online Library
Objectives The aim of the study was to examine baseline neurocognitive impairment (NCI)
prevalence and factors associated with NCI among patients enrolled in the Neurocognitive …

[HTML][HTML] HIV gp120 protein increases the function of connexin 43 hemichannels and pannexin-1 channels in astrocytes: repercussions on astroglial function

R Gajardo-Gómez, CA Santibañez, VC Labra… - International journal of …, 2020 - mdpi.com
At least half of human immunodeficiency virus (HIV)-infected individuals suffer from a wide
range of cognitive, behavioral and motor deficits, collectively known as HIV-associated …

Insights into the Gene Expression Profiles of Active and Restricted Red/Green-HIV+ Human Astrocytes: Implications for Shock or Lock Therapies in the Brain

VV Edara, A Ghorpade, K Borgmann - Journal of virology, 2020 - Am Soc Microbiol
ABSTRACT A significant number of people living with human immunodeficiency virus type 1
(HIV-1) suffer from HIV-associated neurocognitive disorders (HAND). Many previous studies …

Acute transverse myelitis in a HIV-positive patient with COVID-19

V Nemţan, E Manole, E Hacina, G Topciu… - Moldovan Medical …, 2020 - ibn.idsi.md
Background: Immunocompromised status keeps on being a challenge for a physician,
especially in the context of the coronavirus disease–19 (COVID-19) pandemic. The …

Neuro-AIDS: current status and challenges to antiretroviral drug therapy (ART) for its treatment

SP Kakad, SJ Kshirsagar - Current Drug Therapy, 2020 - ingentaconnect.com
Introduction: The infiltration of HIV into the brain alters the functions of the nervous system
known as Neuro-AIDS. It leads to neuronal defects clinically manifested by motor and …

An approach to neurological disorders in a kidney transplant recipient

P Meena, V Bhargava, D Rana, A Bhalla, A Gupta - Kidney360, 2020 - journals.lww.com
Kidney transplantation is the preferred treatment modality in patients with ESKD. However,
there are associated complications that arise from immunosuppressive medications …

[HTML][HTML] A neuron-specific antiviral mechanism modulates the persistent infection of rice rhabdoviruses in leafhopper vectors

H Wang, Y Liu, L Mo, C Huo, Z Wang, P Zhong… - Frontiers in …, 2020 - frontiersin.org
Many plant rhabdoviruses are neurotropic and can persistently infect the central nervous
system (CNS) of their insect vectors without causing significant cytopathology. The …

Evidence for a novel subcortical mechanism for posterior cingulate cortex atrophy in HIV peripheral neuropathy

JR Keltner, A Tong, E Visser, M Jenkinson… - Journal of …, 2020 - Springer
We previously reported that neuropathic pain was associated with smaller posterior
cingulate cortical (PCC) volumes, suggesting that a smaller/dysfunctional PCC may …