Targeting microRNA in hematologic malignancies

Z Han, ST Rosen, C Querfeld - Current opinion in oncology, 2020 - journals.lww.com
Targeting microRNA in hematologic malignancies : Current Opinion in Oncology Targeting
microRNA in hematologic malignancies : Current Opinion in Oncology Log in or Register …

[HTML][HTML] Silencing miR-370-3p rescues funny current and sinus node function in heart failure

J Yanni, A D'Souza, Y Wang, N Li, BJ Hansen… - Scientific reports, 2020 - nature.com
Bradyarrhythmias are an important cause of mortality in heart failure and previous studies
indicate a mechanistic role for electrical remodelling of the key pacemaking ion channel …

Updates on the current technologies for microRNA profiling

R Mathew, V Mattei, M Al Hashmi, S Tomei - Microrna, 2020 - ingentaconnect.com
MicroRNAs are RNA molecules of~ 22 nt length that regulate gene expression
posttranscriptionally. The role of miRNAs has been reported in many cellular processes …

[HTML][HTML] miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells

K Houri, T Mori, Y Onodera, T Tsujimoto, T Takehara… - Scientific reports, 2020 - nature.com
Elevation of the levels of reactive oxygen species (ROS) is a major tissue-degenerative
phenomenon involved in aging and aging-related diseases. The detailed mechanisms …

miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1

T Tsujimoto, T Mori, K Houri, Y Onodera… - Biochemical and …, 2020 - Elsevier
Removal of dysfunctional mitochondria is essential step to maintain normal cell physiology,
and selective autophagy in mitochondria, called mitophagy, plays a critical role in quality …

[HTML][HTML] Expression levels of candidate circulating microRNAs in pediatric tuberculosis

M Kathirvel, S Saranya… - Pathogens and Global …, 2020 - ncbi.nlm.nih.gov
Tuberculosis (TB) is a preventable and curable disease, but increased mortality and
morbidity associated with TB is one of the leading causes of deaths worldwide. MicroRNAs …

MicroRNA expression profiling of lymphoblasts from bipolar disorder patients who died by suicide, pathway analysis and integration with postmortem brain findings

A Squassina, P Niola, JP Lopez, C Cruceanu… - European …, 2020 - Elsevier
Post-mortem brain studies suggest that miRNAs may be involved in suicide, but their role as
peripheral biomarkers or targets of preventive pharmacological treatments in suicide has yet …

[HTML][HTML] Expression profiling of microRNAs and isomiRs in conventional central chondrosarcoma

A Parafioriti, I Cifola, C Gissi, E Pinatel, L Vilardo… - Cell death …, 2020 - nature.com
Conventional central chondrosarcoma (CCC) is a malignant bone tumor that is
characterized by the production of chondroid tissue. Since radiation therapy and …

[HTML][HTML] Nicotine Changes the microRNA Profile to Regulate the FOXO Memory Program of CD8+ T Cells in Rheumatoid Arthritis

C Wasén, C Ospelt, A Camponeschi… - Frontiers in …, 2020 - frontiersin.org
Objective: Smoking suppresses PD-1 expression in patients with rheumatoid arthritis (RA).
In this study, we assess if smoking changed the epigenetic control over CD8+ T cell memory …

MicroRNA expression and correlation with mRNA levels of colorectal cancer-related genes

F Moghadamnia, P Ghoraeian, S Minaeian… - Journal of …, 2020 - Springer
Introduction MicroRNAs (miRNAs), as a family of non-coding RNAs, have opened a new
window in cancer biology and transcriptome. It has been revealed that miRNAs post …