Fibroblasts are cells present throughout the human body that are primarily responsible for
the production and maintenance of the extracellular matrix (ECM) within the tissues. They …

Advances in nanotechnology provided the basis for fabrication of nanoparticulate delivery
systems with large ratios of surface area to volume, rendering them very effective within the …

Shortly after its inception, nanoimprint lithography (NIL) was primarily used as tool for the
thermal embossing and flash curing of thermoplastic resists and polymer precursors …

The development of highly biomimetic scaffolds in terms of composition and structures, to
repair or replace damaged bone tissues, is particularly relevant for tissue engineering. This …

The basement membrane (BM) is a thin specialized extracellular matrix that functions as a
cellular anchorage site, a physical barrier and a signaling hub. While the literature on the …

Circulating rare cells in the blood are of great significance for both materials research and
clinical applications. For example, circulating tumor cells (CTCs) have been demonstrated …

The ability to direct cell behavior has been central to the success of numerous therapeutics
to regenerate tissue or facilitate device integration. Biomaterial scientists are challenged to …

Structured surfaces with both anti-bacterial capability and biocompatibility are essential to
medical devices including orthopedic implants. Over the past few years, numerous studies …

Polyetheretherketone (PEEK) is a promising implant material because of its excellent
mechanical characteristics. Although this polymer is a standard material in spinal …

Peripheral nerve injury is a common and complicated traumatic disease in clinical
neurosurgery. With the rapid advancement and development of medical technologies, novel …