Haptoglobin (Hp) belongs to the family of acute-phase plasma proteins and represents the
most important plasma detoxifier of hemoglobin (Hb). The basic Hp molecule is a tetrameric …

Chagas disease caused by the parasite Trypanosoma cruzi affects millions of people.
Although its first genome dates from 2005, its complexity hindered a complete assembly and …

To clarify the environmental behaviour and bioactivity of epoxiconazole enantiomers, an
integrated assessment has been done. The degradation in soil, water, and river-sediments …

Phosphoglycerate kinase (PGK) is a glycolytic enzyme that is well conserved among the
three domains of life. PGK is usually a monomeric enzyme of about 45 kDa that catalyses …

Despite histone H2A variants and acetylation of histones occurring in almost every
eukaryotic organism, it has been difficult to establish direct functional links between …

Abstract Background The Euglenozoa are a protist group with an especially rich history of
evolutionary diversity. They include diplonemids, representing arguably the most species …

The peritrophic matrix of blood-feeding insects is a chitinous structure that forms a protective
barrier against oral pathogens and abrasive particles. Tsetse flies transmit Trypanosoma …

Proteins of all living cells undergo a myriad of post-translational modifications (PTMs) that
are critical to multifarious life processes. In this study, we describe the first comprehensive …

Detailed comprehensive knowledge of the structures of individual long-range telomere-
terminal haplotypes are needed to understand their impact on telomere function, and to …

Persistent pathogens have evolved to avoid elimination by the mammalian immune system
including mechanisms to evade complement. Infections with African trypanosomes can …