[HTML][HTML] T-Bet expression in peripheral Th17. 0 cells is associated with pulmonary function changes in sarcoidosis

NK Arger, S Machiraju, IE Allen, PG Woodruff… - Frontiers in …, 2020 - frontiersin.org
Background: Interferon-gamma (IFN-γ) is a key mediator of sarcoidosis-related
granulomatous inflammation. Previous findings of IFN-γ-producing Th17 cells in …

[HTML][HTML] Genetic control of CCL24, POR, and IL23R contributes to the pathogenesis of sarcoidosis

A Meguro, M Ishihara, M Petrek, K Yamamoto… - Communications …, 2020 - nature.com
Sarcoidosis is a genetically complex systemic inflammatory disease that affects multiple
organs. We present a GWAS of a Japanese cohort (700 sarcoidosis cases and 886 controls) …

BCG Vaccination of Infants Confers Mycobacterium tuberculosis Strain-Specific Immune Responses by Leukocytes

S Subbian, P Singh, A Kolloli, E Nemes… - ACS infectious …, 2020 - ACS Publications
The efficacy of bacille Calmette–Guerin (BCG) vaccination against tuberculosis is highly
variable, and protective immunity elicited by BCG is poorly understood. We compared the …

[PDF][PDF] Interleukin 12 has an important role in patients infected with Mycobacterium tuberculosis

Q Alfaham, AAJ Aljanaby - International Journal of Pharmaceutical …, 2020 - researchgate.net
Background: Interleukin-12 is a pro-inflammatory cytokine that plays a key role in host
defense against Mycobacterium tuberculosis infection. Materials and methods: A total …

Role of the adaptive immune system in spiral ganglion neuron degeneration after deafening

MT Rahman - 2020 - search.proquest.com
Hearing loss is the most common sensory abnormality. Auditory receptor cell (hair cell) loss
is the most common cause of sensorineural hearing loss. Cochlear implant a neural …