Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …

Over 1.5 million deaths worldwide are caused by neurocardiogenic syndromes.
Furthermore, the consequences of deleterious brain-heart interactions are not limited to fatal …

Stroke is currently one of the most common causes of death and disability in the world, and
its pathophysiology is a complex process, involving the oxidative stress and inflammatory …

Summary Herpes simplex virus (HSV)-1 encephalitis has significant morbidity partly
because of an over-exuberant immune response characterized by leukocyte infiltration into …

Atherosclerosis is responsible for 20% of ischemic strokes, and the plaques from the internal
carotid artery the most frequently involved. Lipoproteins play a key role in carotid …

The immune response to stroke is an exciting target for future stroke therapies. Stroke is a
leading cause of morbidity and mortality worldwide, and clot removal (mechanical or …

Stroke is a heterogeneous disease, and within the broad category of brain ischemia and its
subtypes vary dramatically in its etiology. The endothelium can regulate the vascular …

Preclinical and clinical proof-of-concept studies have suggested the effectiveness of
pharmacological modulation of inflammatory cytokines in ischemic stroke. Experimental …

In stroke (cerebral ischemia), despite continuous efforts both at the experimental and clinical
level, the only approved pharmacological treatment has been restricted to tissue …

Innate immune response is one of our primary defenses against pathogens infection,
although, if dysregulated, it represents the leading cause of chronic tissue inflammation. This …