[HTML][HTML] Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: history, methodology and applications

P Augustijns, M Vertzoni, C Reppas, P Langguth… - European Journal of …, 2020 - Elsevier
Fluid sampling from the gastrointestinal (GI) tract has been applied as a valuable tool to gain
more insight into the fluids present in the human GI tract and to explore the dynamic …

Disposition of two highly permeable drugs in the upper gastrointestinal lumen of healthy adults after a standard high-calorie, high-fat meal

C Pentafragka, M Vertzoni, M Symillides… - European Journal of …, 2020 - Elsevier
Objectives To quantify the presence of two model highly permeable drugs, paracetamol and
danazol, in the upper gastrointestinal lumen under conditions simulating the situation after …

Simultaneous measurement of gastric emptying of a soup test meal using MRI and gamma scintigraphy

A Khalaf, CL Hoad, E Blackshaw, J Alyami, RC Spiller… - Diagnostics, 2020 - mdpi.com
Measurement of gastric emptying is of clinical value for a range of conditions. Gamma
scintigraphy (GS) has an established role, but the use of magnetic resonance imaging (MRI) …

Evaluation of an ileorectostomised rat model for resistant starch determination

DP Belobrajdic, AR Bird - Nutrients, 2020 - mdpi.com
The human ileostomy model, widely considered the benchmark for determining in vivo
starch digestibility, has disadvantages. The ileorectostomised rat model (IRM) is a possible …

Enhancing our understanding of small bowel function using modern imaging techniques

R Spiller, C Hoad - Neurogastroenterology & Motility, 2020 - Wiley Online Library
Small intestinal function is critical to digestive health and patients believe an abnormal
reaction to food is responsible for many of their symptoms. Despite this, our ability to assess …

[PDF][PDF] Evaluation of an Ileorectostomised Rat Model for Resistant Starch Determination. Nutrients 2021, 13, 91

DP Belobrajdic, AR Bird - 2020 - academia.edu
The human ileostomy model, widely considered the benchmark for determining in vivo
starch digestibility, has disadvantages. The ileorectostomised rat model (IRM) is a possible …