Constitutive androstane receptor: a peripheral and a neurovascular stress or environmental sensor
F Oliviero, C Lukowicz, B Boussadia, I Forner-Piquer… - Cells, 2020 - mdpi.com
Xenobiotic nuclear receptors (NR) are intracellular players involved in an increasing number
of physiological processes. Examined and characterized in peripheral organs where they …
of physiological processes. Examined and characterized in peripheral organs where they …
β-catenin signaling, the constitutive androstane receptor and their mutual interactions
A Braeuning, P Pavek - Archives of Toxicology, 2020 - Springer
Aberrant signaling through β-catenin is an important determinant of tumorigenesis in rodents
as well as in humans. In mice, xenobiotic activators of the constitutive androstane receptor …
as well as in humans. In mice, xenobiotic activators of the constitutive androstane receptor …
[HTML][HTML] Overexpression of the constitutive androstane receptor and shaken 3D-culturing increase biotransformation and oxidative phosphorylation and sensitivity to …
VA van der Mark, AAA Adam, JC Chang… - Toxicology and applied …, 2020 - Elsevier
The liver cell line HepaRG is one of the preferred sources of human hepatocytes for in vitro
applications. However, mitochondrial energy metabolism is relatively low, which affects …
applications. However, mitochondrial energy metabolism is relatively low, which affects …