Optogenetics has recently gained recognition as a biological technique to control the activity
of cells using light stimulation. Many studies have applied optogenetics to cell lines in the …

An improved understanding of the mechanisms underlying neuromodulatory approaches to
mitigate seizure onset is needed to identify clinical targets for the treatment of epilepsy …

Somatic mutations have emerged as the likely cause of focal epilepsies associated with
developmental malformations and epilepsy-associated glioneuronal tumors (GNT). Somatic …

Recent experimental literature has revealed that GABAergic interneurons exhibit increased
activity prior to seizure onset, alongside additional evidence that such activity is …

The mouse motor cortex exhibits spontaneous activity in the form of temporal sequences of
neuronal ensembles in vitro without the need of tissue stimulation. These neuronal …

In this work, we introduce new phenomenological neuronal models (e LIF and mAdExp) that
account for energy supply and demand in the cell as well as the inactivation of spike …

In contrast to predictions from the current model of basal ganglia (BG) function, we report
here that increasing inhibition from the BG to the superior colliculus (SC) through the …

We have analyzed the influence of acetylcholine and GABAergic inhibitory transmission on
the functioning of parallel topically organized cortico-basal ganglia–thalamo-cortical neural …

Parvalbumin-expressing interneurons in cortical networks are coupled by gap junctions,
forming a syncytium that supports propagating epileptiform discharges, induced by 4 …

Проведен анализ влияний ацетилхолина и ГАМК-торможения на функционирование
параллельных, топически организованных нейронных цепей новая кора–базальные …