Innovations in 3D tissue models of human brain physiology and diseases
ML Lovett, TJF Nieland, YTL Dingle… - Advanced functional …, 2020 - Wiley Online Library
Abstract 3D laboratory tissue cultures have emerged as an alternative to traditional 2D
culture systems that do not recapitulate native cell behavior. The discrepancy between in …
culture systems that do not recapitulate native cell behavior. The discrepancy between in …
Bioprinting stem cells: building physiological tissues one cell at a time
C Scognamiglio, A Soloperto… - American Journal of …, 2020 - journals.physiology.org
Bioprinting aims to direct the spatial arrangement in three dimensions of cells, biomaterials,
and growth factors. The biofabrication of clinically relevant constructs for the repair or …
and growth factors. The biofabrication of clinically relevant constructs for the repair or …
[HTML][HTML] Functional characterization of three-dimensional cortical cultures for in vitro modeling of brain networks
YTL Dingle, V Liaudanskaya, LT Finnegan, KC Berlind… - IScience, 2020 - cell.com
Summary Three-dimensional (3D) in vitro cultures recapitulate key features of the brain
including morphology, cell-cell and cell-extracellular matrix interactions, gradients of factors …
including morphology, cell-cell and cell-extracellular matrix interactions, gradients of factors …
Retinal and Brain Organoids: Bridging the Gap Between in vivo Physiology and in vitro Micro-Physiology for the Study of Alzheimer's Diseases
C Brighi, F Cordella, L Chiriatti, A Soloperto… - Frontiers in …, 2020 - frontiersin.org
Recent progress in tissue engineering has led to increasingly complex approaches to
investigate human neurodegenerative diseases in vitro, such as Alzheimer's disease …
investigate human neurodegenerative diseases in vitro, such as Alzheimer's disease …
Volumetric Lissajous confocal microscopy with tunable spatiotemporal resolution
Dynamic biological systems present challenges to existing three-dimensional (3D) optical
microscopes because of their continuous temporal and spatial changes. Most techniques …
microscopes because of their continuous temporal and spatial changes. Most techniques …
A new nonlocal nonlinear diffusion equation for data analysis
In this paper we introduce and study a new feature-preserving nonlinear nonlocal diffusion
equation for denoising signals. The proposed partial differential equation is based on a …
equation for denoising signals. The proposed partial differential equation is based on a …
Optonongenetic enhancement of activity in primary cortical neurons
S Ghirga, F Pagani, M Rosito, S Di Angelantonio… - JOSA A, 2020 - opg.optica.org
It has been recently demonstrated that the exposure of naive neuronal cells to light—at the
basis of optogenetic techniques and calcium imaging measurements—may alter neuronal …
basis of optogenetic techniques and calcium imaging measurements—may alter neuronal …