[HTML][HTML] VEGF-A in cardiomyocytes and heart diseases

M Braile, S Marcella, L Cristinziano… - International Journal of …, 2020 - mdpi.com
The vascular endothelial growth factor (VEGF), a homodimeric vasoactive glycoprotein, is
the key mediator of angiogenesis. Angiogenesis, the formation of new blood vessels, is …

Biomaterials for bioprinting microvasculature

RW Barrs, J Jia, SE Silver, M Yost, Y Mei - Chemical reviews, 2020 - ACS Publications
Microvasculature functions at the tissue and cell level, regulating local mass exchange of
oxygen and nutrient-rich blood. While there has been considerable success in the …

Exosomal neurofilament light: A prognostic biomarker for remote symptoms after mild traumatic brain injury?

VA Guedes, K Kenney, P Shahim, BX Qu, C Lai… - Neurology, 2020 - AAN Enterprises
Objective To measure exosomal and plasma levels of candidate blood biomarkers in
veterans with history of mild traumatic brain injury (mTBI) and test their relationship with …

[HTML][HTML] Inflammatory cytokines associate with neuroimaging after acute mild traumatic brain injury

KA Edwards, CL Pattinson, VA Guedes, J Peyer… - Frontiers in …, 2020 - frontiersin.org
Introduction: Elevated levels of blood-based proinflammatory cytokines are linked to acute
moderate to severe traumatic brain injuries (TBIs), yet less is known in acute mild (m) TBI …

Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant …

J Li, X Liu, S Zang, J Zhou, F Zhang, B Sun, D Qi, X Li… - Cancer Letters, 2020 - Elsevier
The blood vessel growth inhibitor bevacizumab targets vascular endothelial growth factor
(VEGF), a crucial regulator of angiogenesis. Recently, small extracellular vesicles (sEVs) …

New aspects of ultrasound-mediated targeted delivery and therapy for cancer

Y Tian, Z Liu, H Tan, J Hou, X Wen… - International Journal of …, 2020 - Taylor & Francis
Ultrasound-mediated targeted delivery (UMTD), a novel delivery modality of therapeutic
materials based on ultrasound, shows great potential in biomedical applications. By …

Neuropilin: Handyman and power broker in the tumor microenvironment

S Niland, JA Eble - Tumor Microenvironment: Signaling Pathways–Part A, 2020 - Springer
Abstract Neuropilin-1 and neuropilin-2 form a small family of transmembrane receptors,
which, due to the lack of a cytosolic protein kinase domain, act primarily as co-receptors for …

Regulation of matrix metalloproteinases 2 and 9 in corneal neovascularization

J Zhang, S Wang, Y He, B Yao… - Chemical Biology & Drug …, 2020 - Wiley Online Library
Corneal neovascularization (CNV), a pathological process of angiogenesis, can lead to
serious consequences in the cornea. CNV is generally proved to associate with …

[HTML][HTML] Activin A triggers angiogenesis via regulation of VEGFA and its overexpression is associated with poor prognosis of oral squamous cell carcinoma

CE De Oliveira, MR Dourado… - International …, 2020 - spandidos-publications.com
Poor prognosis associated with the dysregulated expression of activin A in a number of
malignancies has been related to with numerous aspects of tumorigenesis, including …

The matrisome, inflammation, and liver disease

CE Dolin, GE Arteel - Seminars in liver disease, 2020 - thieme-connect.com
Chronic fatty liver disease is common worldwide. This disease is a spectrum of disease
states, ranging from simple steatosis (fat accumulation) to inflammation, and eventually to …