Cancer is one of the main causes of death worldwide. Despite the significant development of
methods of cancer healing during the past decades, chemotherapy still remains the main …

Background Although neutrophils have been linked to the progression of cancer, uncertainty
exists around their association with cancer outcomes, depending on the site, outcome and …

Background The knowledge that persistent human papillomavirus (HPV) infection is the
main cause of cervical cancer has resulted in the development of prophylactic vaccines to …

Hepatocellular carcinoma is one of the leading causes of cancer related death in the world.
Biannual surveillance for the disease in patients with cirrhosis and in high risk carriers of …

Tumor-associated macrophages (TAMs) are major innate immune cells that constitute up to
50% of the cell mass of human tumors. TAMs are highly heterogeneous cells that originate …

The link between depression and anxiety status and cancer outcomes has been well-
documented but remains unclear. We comprehensively quantified the association between …

Abstract Background N6-methyladenosine (m6A) is the most prevalent RNA epigenetic
regulation in eukaryotic cells. However, understanding of m6A in colorectal cancer (CRC) is …

Metformin is a widely used biguanide drug due to its safety and low cost. It has been used
for over 60 years to treat type 2 diabetes at the early stages because of its outstanding ability …

Background Targeting the programmed cell death protein 1 (PD-1)/programmed cell death
ligand 1 (PD-L1) axis has demonstrated clinical benefit in recurrent/metastatic head and …

Breast cancer is one of the major public health issues and is considered a leading cause of
cancer-related deaths among women worldwide. Its early diagnosis can effectively help in …