From mouse to man and back: closing the correlation gap between imaging and histopathology for lung diseases
B Tielemans, K Dekoster, SE Verleden, S Sawall… - Diagnostics, 2020 - mdpi.com
Lung diseases such as fibrosis, asthma, cystic fibrosis, infection and cancer are life-
threatening conditions that slowly deteriorate quality of life and for which our diagnostic …
threatening conditions that slowly deteriorate quality of life and for which our diagnostic …
In-vivo lung fibrosis staging in a bleomycin-mouse model: a new micro-CT guided densitometric approach
L Mecozzi, M Mambrini, F Ruscitti, E Ferrini… - Scientific reports, 2020 - nature.com
Although increasing used in the preclinical testing of new anti-fibrotic drugs, a thorough
validation of micro-computed tomography (CT) in pulmonary fibrosis models has not been …
validation of micro-computed tomography (CT) in pulmonary fibrosis models has not been …
Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles
L Wu, C Rodríguez-Rodríguez, D Cun, M Yang… - European Journal of …, 2020 - Elsevier
Pulmonary formulations have been attracting much attention because of their direct effects
on respiratory diseases, but also their non-invasive administration for the treatment of …
on respiratory diseases, but also their non-invasive administration for the treatment of …
Assessment of mustard vesicant lung injury and anti‐TNF‐α efficacy in rodents using live‐animal imaging
Nitrogen mustard (NM) causes acute lung injury, which progresses to fibrosis. This is
associated with a macrophage‐dominant inflammatory response and the production of …
associated with a macrophage‐dominant inflammatory response and the production of …
Development of an embedded multimodality imaging platform for onco-pharmacology using a smart anticancer prodrug as an example
F Raes, SM Badiane, B Renoux, S Papot… - Scientific Reports, 2020 - nature.com
Increasingly, in vivo imaging holds a strategic position in bio-pharmaceutical innovation. We
will present the implementation of an integrated multimodal imaging setup enabling the …
will present the implementation of an integrated multimodal imaging setup enabling the …
Deciphering Pulmonary Delivery and Biokinetics of Nanoparticles in Murine Lungs using Novel Imaging Techniques
L Yang - 2020 - mediatum.ub.tum.de
A quantitative in vivo/ex vivo preclinical imaging platform with high temporal (~ 1 Hz) and
multi-scale 3D spatial resolution (down to cellular resolution) is developed and validated for …
multi-scale 3D spatial resolution (down to cellular resolution) is developed and validated for …