Microfluidic systems for hydrodynamic trapping of cells and clusters
Microfluidic devices have been widely applied to trapping and isolation of cells and clusters
for controllable intercellular environments and high-throughput analysis, triggering …
for controllable intercellular environments and high-throughput analysis, triggering …
Progress and prospects in translating nanobiotechnology in medical theranostics
A Batool, F Menaa, B Uzair, BA Khan… - Current …, 2020 - ingentaconnect.com
The pace at which nanotheranostic technology for human disease is evolving has
accelerated exponentially over the past five years. Nanotechnology is committed to utilizing …
accelerated exponentially over the past five years. Nanotechnology is committed to utilizing …
A Precise Microfluidic Assay in Single‐Cell Profile for Screening of Transient Receptor Potential Channel Modulators
X Ai, Y Wu, W Lu, X Zhang, L Zhao, P Tu… - Advanced …, 2020 - Wiley Online Library
Transient receptor potential (TRP) channels are emerging drug targets, and TRP channel
modulators possess therapeutic potential for many indications. However, there is a lack of …
modulators possess therapeutic potential for many indications. However, there is a lack of …
High throughput physiological micro-models for in vitro pre-clinical drug testing: a review of engineering systems approaches
H Zhang, RD Whalley, AM Ferreira… - Progress in Biomedical …, 2020 - iopscience.iop.org
To address the low success rate of new drug discovery, there has been significant growth of
in vitro physiological micro-models based on human cells. These may be in the form of cell …
in vitro physiological micro-models based on human cells. These may be in the form of cell …
Biomaterials and microfluidics for drug discovery and development
MR Carvalho, R Truckenmuller, RL Reis… - … -and Microfluidics-Based …, 2020 - Springer
Microfluidic devices are now one of the most promising tools to mimic in vivo like conditions,
either in normal or disease scenarios, such as tumorigenesis or pathogenesis. Together with …
either in normal or disease scenarios, such as tumorigenesis or pathogenesis. Together with …
Autonomous science: big data tools for small data problems in chemistry
Machine learning tools are emerging to support autonomous science, in which critical
decision-making on experimental design is conducted by algorithms rather than by human …
decision-making on experimental design is conducted by algorithms rather than by human …
Novel criteria for the optimum design of grooved microchannels based on cell shear protection and docking regulation: a lattice Boltzmann method study
Grooved channel bioreactors have shown great applications in cell biology studies by
creating a controlled cellular microenvironment and protecting it from destructive influences …
creating a controlled cellular microenvironment and protecting it from destructive influences …
Microengineered hydrogels for spatially-resolved, multiplexed microRNA quantification from tissue
MB Nagarajan - 2020 - dspace.mit.edu
There is increasing evidence that obtaining both spatially-resolved and multiplexed
measurements of miRNA is critical for diagnostic and prognostic value of miRNA tests. In this …
measurements of miRNA is critical for diagnostic and prognostic value of miRNA tests. In this …