Roles of flavonoids against coronavirus infection

M Russo, S Moccia, C Spagnuolo, I Tedesco… - Chemico-biological …, 2020 - Elsevier
In terms of public health, the 21st century has been characterized by coronavirus
pandemics: in 2002-03 the virus SARS-CoV caused SARS; in 2012 MERS-CoV emerged …

Drug development and medicinal chemistry efforts toward SARS‐coronavirus and Covid‐19 therapeutics

AK Ghosh, M Brindisi, D Shahabi… - …, 2020 - Wiley Online Library
The COVID‐19 pandemic caused by SARS‐CoV‐2 infection is spreading at an alarming
rate and has created an unprecedented health emergency around the globe. There is no …

Learning from the past: possible urgent prevention and treatment options for severe acute respiratory infections caused by 2019‐nCoV

JS Morse, T Lalonde, S Xu, WR Liu - Chembiochem, 2020 - Wiley Online Library
With the current trajectory of the 2019‐nCoV outbreak unknown, public health and medicinal
measures will both be needed to contain spreading of the virus and to optimize patient …

[HTML][HTML] Medicinal plants as sources of active molecules against COVID-19

B Benarba, A Pandiella - Frontiers in pharmacology, 2020 - frontiersin.org
The Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) or novel
coronavirus (COVID-19) infection has been declared world pandemic causing a worrisome …

[HTML][HTML] In silico screening of Chinese herbal medicines with the potential to directly inhibit 2019 novel coronavirus

D Zhang, K Wu, X Zhang, S Deng, B Peng - Journal of integrative medicine, 2020 - Elsevier
Objective In this study we execute a rational screen to identify Chinese medical herbs that
are commonly used in treating viral respiratory infections and also contain compounds that …

[HTML][HTML] Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic

FR Bhuiyan, S Howlader, T Raihan, M Hasan - Frontiers in medicine, 2020 - frontiersin.org
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …

[HTML][HTML] Bioactive natural compounds against human coronaviruses: a review and perspective

Y Xian, J Zhang, Z Bian, H Zhou, Z Zhang, Z Lin… - … Pharmaceutica Sinica B, 2020 - Elsevier
Coronaviruses (CoVs), a family of enveloped positive-sense RNA viruses, are characterized
by club-like spikes that project from their surface, unusually large RNA genome, and unique …

The development of Coronavirus 3C-Like protease (3CLpro) inhibitors from 2010 to 2020

Y Liu, C Liang, L Xin, X Ren, L Tian, X Ju, H Li… - European journal of …, 2020 - Elsevier
This review fully describes the coronavirus 3CL pro peptidomimetic inhibitors and
nonpeptidic small molecule inhibitors developed from 2010 to 2020. Specifically, the …

[HTML][HTML] Potential use of polyphenols in the battle against COVID-19

IL Paraiso, JS Revel, JF Stevens - Current Opinion in Food Science, 2020 - Elsevier
Highlights•Polyphenols interact with SARS-CoV-2 viral proteins and its human cellular
targets.•Virus binding, entry and replication are affected by these plant-derived compounds.• …

In silico pharmacokinetic and molecular docking studies of natural flavonoids and synthetic indole chalcones against essential proteins of SARS-CoV-2

BG Vijayakumar, D Ramesh, A Joji, T Kannan - European journal of …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is distinctly infective and
there is an ongoing effort to find a cure for this pandemic. Flavonoids exist in many diets as …