Melanoma—time to fast or time to feast? An interplay between PPARs, metabolism and immunity

M Grabacka, PM Plonka, K Reiss - Experimental Dermatology, 2020 - Wiley Online Library
Abstract Development and progression of melanoma can be accelerated by intensification of
particular metabolic pathways, such as aerobic glycolysis and avid amino acid catabolism …

The effect of fenofibrate, a PPARα activator on toll-like receptor-4 signal transduction in melanoma both in vitro and in vivo

N Dana, S Haghjooy Javanmard, G Vaseghi - Clinical and Translational …, 2020 - Springer
Background The anti-cancer effect of peroxisome proliferator-activated receptor (PPAR) α
ligands on growth and metastatic potential of melanoma cells has been shown previously …

Genetic variants in PDSS1 and SLC16A6 of the ketone body metabolic pathway predict cutaneous melanoma‐specific survival

W Dai, H Liu, K Chen, X Xu, D Qian… - Molecular …, 2020 - Wiley Online Library
A few single‐nucleotide polymorphisms (SNPs) have been identified to be associated with
cutaneous melanoma (CM) survival through genome‐wide association studies, but stringent …