Immunity, hypoxia, and metabolism–the Ménage à Trois of cancer: implications for immunotherapy
C Riera-Domingo, A Audigé, S Granja… - Physiological …, 2020 - journals.physiology.org
It is generally accepted that metabolism is able to shape the immune response. Only
recently we are gaining awareness that the metabolic crosstalk between different tumor …
recently we are gaining awareness that the metabolic crosstalk between different tumor …
Crucial players in glycolysis: cancer progress
Cancer is the second most important cause of death and new therapy modalities continue to
be developed and evolved. Cancer cells' metabolism is far different from the normal, healthy …
be developed and evolved. Cancer cells' metabolism is far different from the normal, healthy …
[HTML][HTML] Metabolic plasticity in chemotherapy resistance
MA Desbats, I Giacomini, T Prayer-Galetti… - Frontiers in …, 2020 - frontiersin.org
Resistance of cancer cells to chemotherapy is the first cause of cancer-associated death.
Thus, new strategies to deal with the evasion of drug response and to improve clinical …
Thus, new strategies to deal with the evasion of drug response and to improve clinical …
[HTML][HTML] Lactic acidosis interferes with toxicity of perifosine to colorectal cancer spheroids: multimodal imaging analysis
B Pavlatovská, M Machálková, P Brisudová… - Frontiers in …, 2020 - frontiersin.org
Colorectal cancer (CRC) is a disease with constantly increasing incidence and high
mortality. The treatment efficacy could be curtailed by drug resistance resulting from poor …
mortality. The treatment efficacy could be curtailed by drug resistance resulting from poor …
Pretreatment serum neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios: Two tumor-related systemic inflammatory markers in patients with thymic epithelial …
L Wang, M Ruan, H Yan, B Lei, X Sun, C Chang, L Liu… - Cytokine, 2020 - Elsevier
Objectives To understand underlying changes in pretreatment serum inflammatory markers
associated with thymic epithelial tumors (TETs) development. Methods A retrospective …
associated with thymic epithelial tumors (TETs) development. Methods A retrospective …
Autophagy driven extracellular vesicles in the leukaemic microenvironment
RH Horton, T Wileman… - Current Cancer Drug …, 2020 - ingentaconnect.com
The leukaemias are a heterogeneous group of blood cancers, which together, caused
310,000 deaths in 2016. Despite significant research into their biology and therapeutics …
310,000 deaths in 2016. Despite significant research into their biology and therapeutics …
[HTML][HTML] Exploiting Cancer's tactics to make cancer a manageable chronic disease
K Afrasiabi, ME Linskey, YH Zhou - Cancers, 2020 - mdpi.com
The history of modern oncology started around eighty years ago with the introduction of
cytotoxic agents such as nitrogen mustard into the clinic, followed by multi-agent …
cytotoxic agents such as nitrogen mustard into the clinic, followed by multi-agent …
Recent advances in drug development targeting cancer metabolism
Cancer cell proliferation and their adaptation to tough environments depend critically on
metabolic pathways. The pathological, phenotypic, and structural level understanding of …
metabolic pathways. The pathological, phenotypic, and structural level understanding of …