Viral subversion of nonsense-mediated mRNA decay

MWL Popp, H Cho, LE Maquat - Rna, 2020 - rnajournal.cshlp.org
Viruses have evolved in tandem with the organisms that they infect. Afflictions of the plant
and animal kingdoms with viral infections have forced the host organism to evolve new or …

Recurrent SRSF2 mutations in MDS affect both splicing and NMD

MA Rahman, KT Lin, RK Bradley… - Genes & …, 2020 - genesdev.cshlp.org
Oncogenic mutations in the RNA splicing factors SRSF2, SF3B1, and U2AF1 are the most
frequent class of mutations in myelodysplastic syndromes and are also common in clonal …

[PDF][PDF] CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex

JV Gerbracht, V Boehm, T Britto-Borges… - Nucleic Acids …, 2020 - academic.oup.com
The exon junction complex (EJC) is an essential constituent and regulator of spliced
messenger ribonucleoprotein particles (mRNPs) in metazoans. As a core component of the …

DDX56 binds to chikungunya virus RNA to control infection

F Taschuk, I Tapescu, RH Moy, S Cherry - MBio, 2020 - Am Soc Microbiol
ABSTRACT DEAD box RNA helicases regulate diverse facets of RNA biology. Proteins of
this family carry out essential cellular functions, and emerging literature is revealing …

NCBP3 positively impacts mRNA biogenesis

Y Dou, I Barbosa, H Jiang, C Iasillo… - Nucleic Acids …, 2020 - academic.oup.com
Abstract The nuclear Cap-Binding Complex (CBC), consisting of Nuclear Cap-Binding
Protein 1 (NCBP1) and 2 (NCBP2), associates with the nascent 5′ cap of RNA polymerase …

[PDF][PDF] DDX56 binds to chikungunya virus RNA to control infection. mBio 11: e02623-20

F Taschuk, I Tapescu, RH Moy, S Cherry - PMC7593974, 2020 - academia.edu
ABSTRACT DEAD box RNA helicases regulate diverse facets of RNA biology. Proteins of
this family carry out essential cellular functions, and emerging literature is revealing …

Translation and post-translational modifications in protein biosynthesis

CT Mierke, CT Mierke - Cellular Mechanics and Biophysics: Structure and …, 2020 - Springer
The experimental methods employed to analyze living systems and the obtained data are
usually quantitative. Thus, the investigation of the process of translation and the post …

NCBP3 is a productive mRNP component

Y Dou, I Barbosa, H Jiang, C Iasillo, KR Molloy… - bioRxiv, 2020 - biorxiv.org
Abstract The nuclear Cap Binding Complex (CBC), consisting of Nuclear Cap Binding
Protein 1 (NCBP1) and 2 (NCBP2), associates with the nascent 5'cap of RNA polymerase II …

[图书][B] The Dynamic Fate of the Exon Junction Complex

RD Patton - 2020 - search.proquest.com
Abstract The Exon Junction Complex, or EJC, is a group of proteins deposited on mRNA
upstream of exon-exon junctions during splicing, and which stays with the mRNA up until …

CASC3 depletion in HEK293 cells causes upregulation of NMD-sensitive mRNA Transcripts

MB Bulimaga - Sesiune națională cu participare internațională de …, 2020 - ibn.idsi.md
The exon junction complex (EJC) is a protein complex composed of four core components-
EIF4A3, RBM8A, MAGOH, and CASC3and several peripheral components. During splicing …