Animals that lack the hormone leptin become grossly obese, purportedly for 2 reasons:
increased food intake and decreased energy expenditure (thermogenesis). This review …

Obesity and its associated metabolic diseases are currently a priority research area. The
increase in global prevalence at different ages is having an enormous economic and health …

Background: Activation of the thermogenic program in white and brown adipocytes presents
a promising avenue for increasing energy expenditure during the treatment of obesity. The …

Leptin is a hormone released by adipose tissue that plays a key role in the control of energy
homeostasis through its binding to leptin receptors (LepR), mainly expressed in the …

Background: The incidence of intraoperative hypothermia is still high despite the proposal of
different preventive measures during thoracoscopic surgery. This randomized control study …

Excessive adipose accumulation, which is the main driver for the development of secondary
metabolic complications, has reached epidemic proportions and combined pharmaceutical …

Abstract Purpose of Review To summarize the state-of-the-art regarding the exercise-
regulated endocrine signals that might modulate brown adipose tissue (BAT) activity and/or …

Long-chain ω-3 polyunsaturated fatty acids (PUFAs) are fundamental biocomponents of
lipids and cell membranes. They are involved in the maintenance of cellular homeostasis …

Growing female mice housed at room temperature (22° C) weigh the same but differ in body
composition compared to mice housed at thermoneutrality (32° C). Specifically, mice housed …

Central action of the adipocyte hormone leptin via the neuropeptide Y (NPY) system is
considered critical for energy homeostatic control. However, the precise mechanisms for this …