[HTML][HTML] Club cell secreted protein CC16: potential applications in prognosis and therapy for pulmonary diseases

S Almuntashiri, Y Zhu, Y Han, X Wang… - Journal of clinical …, 2020 - mdpi.com
Club cell secretory protein (CC16) is encoded by the SCGB1A1 gene. It is also known as
CC10, secretoglobin, or uteroglobin. CC16 is a 16 kDa homodimeric protein secreted …

[HTML][HTML] Time to say goodbye to bronchiolitis, viral wheeze, reactive airways disease, wheeze bronchitis and all that

K Douros, ML Everard - Frontiers in pediatrics, 2020 - frontiersin.org
The diagnosis and management of infants and children with a significant viral lower
respiratory tract illness remains the subject of much debate and little progress. Over the …

The genetic epidemiology of pediatric pulmonary arterial hypertension

MG Haarman, WS Kerstjens-Frederikse… - The Journal of …, 2020 - Elsevier
Objective To describe the prevalence of pulmonary arterial hypertension (PAH)-associated
gene mutations, and other genetic characteristics in a national cohort of children with PAH …

Atractylenolide III attenuates bleomycin-induced experimental pulmonary fibrosis and oxidative stress in rat model via Nrf2/NQO1/HO-1 pathway activation

B Huai, J Ding - Immunopharmacology and Immunotoxicology, 2020 - Taylor & Francis
Background Bleomycin (BLM) is a chemotherapy drug used to treat cancer, one of which
side effects is that it can lead to pulmonary fibrosis (PF). Atractylenoide III (AtrIII), derived …

Functional assessment and phenotypic heterogeneity of SFTPA1 and SFTPA2 mutations in interstitial lung diseases and lung cancer

M Legendre, A Butt, R Borie, MP Debray… - European …, 2020 - Eur Respiratory Soc
Introduction Interstitial lung diseases (ILDs) can be caused by mutations in the SFTPA1 and
SFTPA2 genes, which encode the surfactant protein (SP) complex SP-A. Only 11 SFTPA1 or …

[HTML][HTML] Testing for lipid-laden macrophages in bronchoalveolar lavage fluid to diagnose vaping-associated pulmonary injury. Are we there yet?

SE Pambuccian - Journal of the American Society of Cytopathology, 2020 - Elsevier
Vaping-associated pulmonary injury (VAPI) is a severe respiratory disorder associated with
the inhalation of nicotine, tetrahydrocannabinol, cannabidiol, or other active substances …

Interstitial lung diseases in children

N Nathan, L Berdah, C Delestrain, C Sileo… - La Presse Médicale, 2020 - Elsevier
Interstitial lung disease (ILD) in children (chILD) is a heterogeneous group of rare respiratory
disorders that are mostly chronic and associated with high morbidity and mortality. The …

[HTML][HTML] Children's interstitial and diffuse lung diseases (chILD) in 2020

VA Ferraro, S Zanconato, A Zamunaro, S Carraro - Children, 2020 - mdpi.com
The term children interstitial lung diseases (chILD) refers to a heterogeneous group of rare
diseases that diffusely affect the lung. ChILD specific to children younger than 2 years of age …

Protein misfolding and endoplasmic reticulum stress in chronic lung disease: will cell-specific targeting be the key to the cure?

S Naiel, V Tat, M Padwal, M Vierhout, O Mekhael… - Chest, 2020 - Elsevier
Chronic lung disease accounts for a significant global burden with respect to death,
disability, and health-care costs. Due to the heterogeneous nature and limited treatment …

[HTML][HTML] TBX4 variants and pulmonary diseases: getting out of the 'Box'

MG Haarman, WS Kerstjens-Frederikse… - Current opinion in …, 2020 - journals.lww.com
The clinical phenotype of a TBX4 variant has recently been recognised to expand from bone
disorders to different types of lung diseases. Recent data suggest that variants of TBX4, a …