Biology and pathogenesis of human osteosarcoma
JWV de Azevedo, TAAM Fernandes… - Oncology …, 2020 - spandidos-publications.com
Osteosarcoma (OS) is a bone tumor of mesenchymal origin, most frequently occurring
during the rapid growth phase of long bones, and usually located in the epiphyseal growth …
during the rapid growth phase of long bones, and usually located in the epiphyseal growth …
Understanding and modeling metastasis biology to improve therapeutic strategies for combating osteosarcoma progression
TM Fan, RD Roberts, MM Lizardo - Frontiers in oncology, 2020 - frontiersin.org
Osteosarcoma is a malignant primary tumor of bone, arising from transformed progenitor
cells with osteoblastic differentiation and osteoid production. While categorized as a rare …
cells with osteoblastic differentiation and osteoid production. While categorized as a rare …
COVID-19–Induced modifications in the tumor microenvironment: do they affect cancer reawakening and metastatic relapse?
F Francescangeli, ML De Angelis, M Baiocchi… - Frontiers in …, 2020 - frontiersin.org
Severe coronavirus disease 2019 (COVID-19) causes an uncontrolled activation of the
innate immune response, resulting in acute respiratory distress syndrome and systemic …
innate immune response, resulting in acute respiratory distress syndrome and systemic …
GD2‐directed CAR‐T cells in combination with HGF‐targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing sarcoma
Ewing sarcoma (EWS) is the second most common and aggressive type of metastatic bone
tumor in adolescents and young adults. There is unmet medical need to develop and test …
tumor in adolescents and young adults. There is unmet medical need to develop and test …
The interaction of interleukin-8 and PTEN inactivation promotes the malignant progression of head and neck squamous cell carcinoma via the STAT3 pathway
Q Xu, H Ma, H Chang, Z Feng, C Zhang, X Yang - Cell death & disease, 2020 - nature.com
Abstract Interleukin-8 (IL-8) expression correlates with poor prognosis in many cancers,
including head and neck squamous cell carcinoma (HNSCC), but the underlying …
including head and neck squamous cell carcinoma (HNSCC), but the underlying …
Identification of key genes and pathways of diagnosis and prognosis in cervical cancer by bioinformatics analysis
H Yang, J Xue, J Li, L Wan, Y Zhu - Molecular Genetics & …, 2020 - Wiley Online Library
Background Cervical cancer as one of the most common malignant tumors lead to bad
prognosis among women. Some researches already focus on the carcinogenesis and …
prognosis among women. Some researches already focus on the carcinogenesis and …
[HTML][HTML] Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling …
The pre-metastatic niche (PMN) represents an abnormal microenvironment devoid of cancer
cells, but favoring tumor growth. Little is known about the mechanisms that generate the …
cells, but favoring tumor growth. Little is known about the mechanisms that generate the …
Nanomedicine in osteosarcoma therapy: Micelleplexes for delivery of nucleic acids and drugs toward osteosarcoma-targeted therapies
M Pereira-Silva, C Alvarez-Lorenzo… - European Journal of …, 2020 - Elsevier
Osteosarcoma (OS) represents the main cancer affecting bone tissue, and one of the most
frequent in children. In this review we discuss the major pathological hallmarks of this …
frequent in children. In this review we discuss the major pathological hallmarks of this …
Gene prioritization through consensus strategy, enrichment methodologies analysis, and networking for osteosarcoma pathogenesis
A Cabrera-Andrade, A López-Cortés… - International journal of …, 2020 - mdpi.com
Osteosarcoma is the most common subtype of primary bone cancer, affecting mostly
adolescents. In recent years, several studies have focused on elucidating the molecular …
adolescents. In recent years, several studies have focused on elucidating the molecular …