Interactions of the choroid, Bruch's membrane, retinal pigment epithelium, and neurosensory retina collaborate to form the outer blood-retinal-barrier

MA Fields, LV Del Priore, RA Adelman… - Progress in retinal and …, 2020 - Elsevier
The three interacting components of the outer blood-retinal barrier are the retinal pigment
epithelium (RPE), choriocapillaris, and Bruch's membrane, the extracellular matrix that lies …

Claudin-1, a double-edged sword in cancer

AA Bhat, N Syed, L Therachiyil, S Nisar… - International journal of …, 2020 - mdpi.com
Claudins, a group of membrane proteins involved in the formation of tight junctions, are
mainly found in endothelial or epithelial cells. These proteins have attracted much attention …

Targeting claudin‐overexpressing thyroid and lung cancer by modified Clostridium perfringens enterotoxin

A Piontek, M Eichner, D Zwanziger, LS Beier… - Molecular …, 2020 - Wiley Online Library
Clostridium perfringens enterotoxin (CPE) can be used to eliminate carcinoma cells that
overexpress on their cell surface CPE receptors–a subset of claudins (eg, Cldn3 and Cldn4) …

Claudins: new players in human fertility and reproductive system cancers

MJ Kozieł, K Kowalska, AW Piastowska-Ciesielska - Cancers, 2020 - mdpi.com
Claudins are major integral proteins of tight junctions (TJs), the apical cell–cell adhesions
that enable maintaining polarity of epithelial cells, their differentiation, and cell signaling. A …

E7 oncoprotein from human papillomavirus 16 alters claudins expression and the sealing of epithelial tight junctions

PY Uc, J Miranda, A Raya-Sandino… - International …, 2020 - spandidos-publications.com
Tight junctions (TJs) are cell-cell adhesion structures frequently altered by oncogenic
transformation. In the present study the role of human papillomavirus (HPV) 16 E7 …