The process of bone remodeling is the result of the regulated balance between bone cell
populations, namely bone-forming osteoblasts, bone-resorbing osteoclasts, and the …

Vital osteocytes have been well known to function as an important orchestrator in the
preservation of robustness and fidelity of the bone remodeling process. Nevertheless, some …

Iron overload is closely associated with osteoporosis, the potential cellular mechanism
involved in decreased osteoblast differentiation and increased osteoclast formation …

We review evidence supporting an updated mechanostat model in bone that highlights the
central role of osteocytes within bone's four mechanoadaptive pathways: 1) formation …

Localized apoptosis of osteocytes, the tissue‐resident cells within bone, occurs with fatigue
microdamage and activates bone resorption. Osteoclasts appear to target and remove dying …

Bone loss has been supposed to be the greatest damage to the health of astronauts. It is
generally believed that the mechanical unloading induced by microgravity is the main cause …

Although the impact of osteoblast-osteoclast crosstalk in bone remodelling has been
intensively studied, the importance of osteocytes, descendants of osteoblasts, in this process …

Background and purpose—Insufficient initial fixation or early micromotion of an implant is
associated with a thin layer of fibrous tissue at the peri-implant interface. It is unknown if …

Osteoclastogenesis required for bone remodeling is also a key pathologic mechanism of
inflammatory osteolysis being controlled by paracrine factors released from dying cells. The …

The endothelin system has an important role in bone modelling during orthodontic tooth
movement (OTM); however, little is known about the involvement of endothelin B receptors …