From design to applications of stimuli-responsive hydrogel strain sensors
Stimuli-responsive hydrogel strain sensors that synergize the advantages of both soft-wet
hydrogels and smart functional materials have attracted rapidly increasing interest for …
hydrogels and smart functional materials have attracted rapidly increasing interest for …
Rationally designed multivalent aptamers targeting cell surface for biomedical applications
Specific interactions between ligands and receptors on cell surface play an important role in
the cell biological process. Nucleic acid aptamers as commonly used ligands enable …
the cell biological process. Nucleic acid aptamers as commonly used ligands enable …
Fluidic multivalent membrane nanointerface enables synergetic enrichment of circulating tumor cells with high efficiency and viability
The ubiquitous biomembrane interface, with its dynamic lateral fluidity, allows membrane-
bound components to rearrange and localize for high-affinity multivalent ligand–receptor …
bound components to rearrange and localize for high-affinity multivalent ligand–receptor …
Programming cell–cell communications with engineered cell origami clusters
Cells existing in the form of clusters often exhibit distinct physiological functions from their
monodispersed forms, which have a close association with tissue and organ development …
monodispersed forms, which have a close association with tissue and organ development …
Bioinspired DNA nanointerface with anisotropic aptamers for accurate capture of circulating tumor cells
W Qin, L Chen, Z Wang, Q Li, C Fan, M Wu… - Advanced …, 2020 - Wiley Online Library
The capture and analysis of circulating tumor cells (CTCs) have provided a non‐invasive
entry for cancer diagnosis and disease monitoring. Despite recent development in affinity …
entry for cancer diagnosis and disease monitoring. Despite recent development in affinity …
Ultrafast DNA sensors with DNA framework-bridged hybridization reactions
Intracellular DNA-based hybridization reactions generally occur under tension rather than in
free states, which are spatiotemporally controlled in physiological conditions. However, how …
free states, which are spatiotemporally controlled in physiological conditions. However, how …
DNA Framework‐Based Topological Cell Sorters
Molecular recognition in cell biological process is characterized with specific locks‐and‐
keys interactions between ligands and receptors, which are ubiquitously distributed on cell …
keys interactions between ligands and receptors, which are ubiquitously distributed on cell …
Aptamer-based liquid biopsy
L Wu, Y Wang, L Zhu, Y Liu, T Wang, D Liu… - ACS applied bio …, 2020 - ACS Publications
Liquid biopsy allows noninvasive and real-time analysis of tumor-derived circulating targets
in body fluids, holding great value for cancer diagnosis, prognosis, personalized therapy, as …
in body fluids, holding great value for cancer diagnosis, prognosis, personalized therapy, as …
Extracellular ion-responsive logic sensors utilizing DNA dimeric nanoassemblies on cell surface and application to boosting AS1411 internalization
P Peng, Q Wang, Y Du, H Wang, L Shi, T Li - Analytical Chemistry, 2020 - ACS Publications
High levels of extracellular H+ and K+ are unique features of the tumor microenvironment
and have shown great promise for use in cancer-targeted drug delivery. Here, we design H+ …
and have shown great promise for use in cancer-targeted drug delivery. Here, we design H+ …
Designer, programmable 3D DNA nanodevices to probe biological systems
A Rajwar, S Kharbanda… - ACS Applied Bio …, 2020 - ACS Publications
DNA nanotechnology is a unique field that provides simple yet robust design techniques for
self-assembling nanoarchitectures with extremely high potential for biomedical applications …
self-assembling nanoarchitectures with extremely high potential for biomedical applications …