Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update
Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …
Prospects for RNAi therapy of COVID-19
H Uludağ, K Parent, HM Aliabadi… - … in Bioengineering and …, 2020 - frontiersin.org
COVID-19 caused by the SARS-CoV-2 virus is a fast emerging disease with deadly
consequences. The pulmonary system and lungs in particular are most prone to damage …
consequences. The pulmonary system and lungs in particular are most prone to damage …
Antiproliferative effects of boswellic acid-loaded chitosan nanoparticles on human lung cancer cell line A549
N Solanki, M Mehta, DK Chellappan… - Future medicinal …, 2020 - Taylor & Francis
Aim: In the present study boswellic acids-loaded chitosan nanoparticles were synthesized
using ionic gelation technique. The influence of independent variables were studied and …
using ionic gelation technique. The influence of independent variables were studied and …
Perspectives and advancements in the design of nanomaterials for targeted cancer theranostics
Cancer continues to be one of the most challenging diseases to be treated and is one of the
leading causes of deaths around the globe. Cancers account for 13% of all deaths each …
leading causes of deaths around the globe. Cancers account for 13% of all deaths each …
Solid lipid nanoparticles containing anti-tubercular drugs attenuate the Mycobacterium marinum infection
The present study aimed to formulate anti-tubercular drugs (Rifampicin, Isoniazid and
Pyrazinamide) loaded solid lipid nanoparticles (ATDs-SLNs) using microemulsion technique …
Pyrazinamide) loaded solid lipid nanoparticles (ATDs-SLNs) using microemulsion technique …
Molecular mechanisms of action of naringenin in chronic airway diseases
LH Chin, CM Hon, DK Chellappan, J Chellian… - European journal of …, 2020 - Elsevier
Chronic airway inflammatory diseases are characterized by persistent proinflammatory
responses in the respiratory tract. Although, several treatment strategies are currently …
responses in the respiratory tract. Although, several treatment strategies are currently …
Therapeutic RNA strategies for chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation with
persistent respiratory symptoms. Current therapeutics for COPD are largely borrowed from …
persistent respiratory symptoms. Current therapeutics for COPD are largely borrowed from …
Protective role of poly (lactic‐co‐glycolic) acid nanoparticle loaded with resveratrol against isoproterenol‐induced myocardial infarction
L Sun, Y Hu, A Mishra, N Sreeharsha, JB Moktan… - Biofactors, 2020 - Wiley Online Library
Our study is aimed at evaluating the effects of pretreatment with Poly (lactic‐co‐glycolic) acid
nanoparticle loaded with resveratrol (RSV PLGA NPs) compared to conventional resveratrol …
nanoparticle loaded with resveratrol (RSV PLGA NPs) compared to conventional resveratrol …
RNAi therapeutics: an antiviral strategy for human infections
Highlights•RNAi is a promising antiviral development strategy.•Pathways include classic
RNAi (mRNA target) and novel RNAi (promoter target).•Most RNAi therapeutics act via …
RNAi (mRNA target) and novel RNAi (promoter target).•Most RNAi therapeutics act via …
Advanced drug delivery systems can assist in managing influenza virus infection: A hypothesis
Outbreaks of influenza infections in the past have severely impacted global health and
socioeconomic growth. Antivirals and vaccines are remarkable medical innovations that …
socioeconomic growth. Antivirals and vaccines are remarkable medical innovations that …