The role of pharmacogenomics in the personalization of Parkinson's disease treatment

S Redenšek, V Dolžan - Pharmacogenomics, 2020 - Future Medicine
Parkinson's disease (PD)-related phenotypes can vary among patients substantially,
including response to dopaminergic treatment in terms of efficacy and occurrence of adverse …

Gene polymorphisms and motor levodopa‐induced complications in Parkinson's disease

M Michałowska, M Chalimoniuk, E Jówko… - Brain and …, 2020 - Wiley Online Library
Objective The aim of the study was to evaluate the association of individual and combined
single‐nucleotide polymorphisms in brain‐derived neurotrophic factor (BDNF), dopamine …

Pharmacogenetic profile and the development of the dyskinesia induced by levodopa-therapy in Parkinson's disease patients: a population-based cohort study

EUD Dos Santos, IIFG da Silva, AGC Asano… - Molecular Biology …, 2020 - Springer
Levodopa-induced dyskinesia (LID) is an adverse effect that negatively impacts the quality
of life of patients with Parkinson's disease (PD). Studies report that genetic variations in the …

Development of a COMT PCR multiplex to investigate resilience, anxiety and childhood trauma in a South African population

S Jacobs - 2020 - etd.uwc.ac.za
Anxiety, resilience and childhood trauma can be categorized as functional behavioural
categories, with a wealth of research behind each. The research approach adopted for each …