Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

S Bangaru, G Ozorowski, HL Turner, A Antanasijevic… - Science, 2020 - science.org
Vaccine efforts to combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), which is responsible for the current coronavirus disease 2019 (COVID-19) pandemic, are …

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

A Antanasijevic, G Ueda, PJM Brouwer, J Copps… - PLoS …, 2020 - journals.plos.org
Two-component, self-assembling nanoparticles represent a versatile platform for multivalent
presentation of viral antigens. Computational design of protein nanoparticles with differing …

Immunogenicity and immunodominance in antibody responses

M Vogel, MF Bachmann - Vaccination Strategies Against Highly Variable …, 2020 - Springer
A large number of vaccines exist that control many of the most important infectious diseases.
Despite these successes, there remain many pathogens without effective prophylactic …

Structurally distinct endocytic pathways for B cell receptors in B lymphocytes

AD Roberts, TM Davenport, AM Dickey… - Molecular Biology of …, 2020 - Am Soc Cell Biol
B lymphocytes play a critical role in adaptive immunity. On antigen binding, B cell receptors
(BCR) cluster on the plasma membrane and are internalized by endocytosis. In this process …