Conventional chemotherapeutics have been developed into clinically useful agents based
on their ability to preferentially kill malignant cells, generally owing to their elevated …

Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …

Chemotherapy, radiation therapy, as well as targeted anticancer agents can induce clinically
relevant tumor-targeting immune responses, which critically rely on the antigenicity of …

Ovarian cancer is the most lethal gynecologic malignancy. Surgery and chemotherapy are
the primary treatments for ovarian cancer; however, patients often succumb to recurrence …

A wealth of evidence supports the role of tumor immunotherapy as a vital therapeutic option
in cancer. In recent decades, accumulated studies have revealed the anticancer activities of …

The term 'immunogenic cell death'(ICD) denotes an immunologically unique type of
regulated cell death that enables, rather than suppresses, T cell-driven immune responses …

Cell death resistance is a key feature of tumor cells. One of the main anticancer therapies is
increasing the susceptibility of cells to death. Cancer cells have developed a capability of …

Saponins are amphiphilic molecules consisting of carbohydrate and either triterpenoid or
steroid aglycone moieties and are noted for their multiple biological activities—Fungicidal …

Immunogenic cell death (ICD) is a rare immunostimulatory form of cell death that can
improve the clinical outcomes of chemo‐immunotherapeutic combination regimens through …

Current cancer immunotherapy has limited response rates in a large variety of solid tumors
partly due to the low immunogenicity of the tumor cells and the immunosuppressive tumor …