Background Neonatal hypoxic ischaemic encephalopathy due to perinatal asphyxia, can
result in severe neurodevelopmental disability or mortality. Hypothermia is at present the …

Morphine is the opioid most commonly used for neonatal pain management. In intravenous
form, it is administered as continuous infusions and intermittent injections, mostly based on …

We have previously reported the influences of OCT1 ontogeny and genetic variation on
morphine clearance in neonatal and pediatric patients. In the latter study, plasma morphine …

Background: Pain control in infants is an important clinical concern, with potential long-term
adverse neurodevelopmental effects. Intravenous morphine is routinely administered for …

Titrating analgesic and sedative drugs in pediatric intensive care remains a challenge for
caregivers due to the lack of pharmacodynamic knowledge in this population. The aim of the …

Αρχικά, θα ήθελα να εκφράσω τη βαθιά ευγνωμοσύνη μου προς τον επιβλέποντα της
διδακτορικής διατριβής, Καθηγητή Παιδιατρικής-Λοιμωξιολογίας της Ιατρικής Σχολής ΑΠΘ κ …