Call to action regarding the vascular‐bipolar link: a report from the Vascular Task Force of the International Society for Bipolar Disorders

BI Goldstein, BT Baune, DJ Bond, PH Chen… - Bipolar …, 2020 - Wiley Online Library
Objectives The association of bipolar disorder with early and excessive cardiovascular
disease was identified over a century ago. Nonetheless, the vascular‐bipolar link remains …

[HTML][HTML] Improvements of symptoms of Alzheimers disease by inhibition of the angiotensin system

U Quitterer, S AbdAlla - Pharmacological research, 2020 - Elsevier
With ageing of the global society, the frequency of ageing-related neurodegenerative
diseases such as Alzheimers disease (AD) is on the rise worldwide. Currently, there is no …

Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal

PJ Harrison, EM Tunbridge, AC Dolphin… - The British Journal of …, 2020 - cambridge.org
We reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-
gated calcium channels are risk genes for several disorders. Second, use of CCBs is …

Angiotensin-converting enzyme inhibitor rapidly ameliorates depressive-type behaviors via bradykinin-dependent activation of mammalian target of rapamycin …

H Luo, PF Wu, Y Cao, M Jin, TT Shen, J Wang… - Biological …, 2020 - Elsevier
Background Angiotensin-converting enzyme inhibitors (ACEIs) are widely prescribed
antihypertensive agents. Intriguingly, case reports and clinical trials have indicated that …

Rates of delirium associated with calcium channel blockers compared to diuretics, renin-angiotensin system agents and beta-blockers: an electronic health records …

PJ Harrison, S Luciano… - Journal of …, 2020 - journals.sagepub.com
Background: Antihypertensive drugs, especially calcium channel blockers, have been
associated with differential rates of a number of neuropsychiatric outcomes. Delirium is …

The association of antihypertensive use and depressive symptoms in a large older population with hypertension living in Australia and the United States: a cross …

B Agustini, M Mohebbi, RL Woods, JJ McNeil… - Journal of human …, 2020 - nature.com
Cardiovascular drugs impact many pathways involved in depression pathophysiology and
treatment. However, their distinct impact on mood is underrecognized and the literature is …

Targeting the renin angiotensin system for the treatment of anxiety and depression

S Chrissobolis, AN Luu, RA Waldschmidt… - Pharmacology …, 2020 - Elsevier
Emotional disorders like anxiety and depression are responsible for considerable morbidity
and mortality all over the world. Several antidepressant and anxiolytic medications are …

Exploring the evidence implicating the renin-angiotensin system (RAS) in the physiopathology of mood disorders

S Mohite, M Sanches, AL Teixeira - Protein and Peptide Letters, 2020 - ingentaconnect.com
Mood disorders include Major Depressive Disorder (MDD), Bipolar Disorder (BD) and
variations of both. Mood disorders has a public health significance with high comorbidity …

Prediction of major depressive disorder following beta-blocker therapy in patients with cardiovascular diseases

S Jin, K Kostka, JD Posada, Y Kim, SI Seo… - Journal of personalized …, 2020 - mdpi.com
Incident depression has been reported to be associated with poor prognosis in patients with
cardiovascular disease (CVD), which might be associated with beta-blocker therapy …

Depression as an immunometabolic disorder: exploring shared pharmacotherapeutics with cardiovascular disease

M Chávez-Castillo, M Nava, Á Ortega… - Current …, 2020 - ingentaconnect.com
Modern times have seen depression and cardiovascular disease (CVD) become notorious
public health concerns, corresponding to alarming proportions of morbidity, mortality …