Recent advances in mass spectrometry based clinical proteomics: applications to cancer research

A Macklin, S Khan, T Kislinger - Clinical proteomics, 2020 - Springer
Cancer biomarkers have transformed current practices in the oncology clinic. Continued
discovery and validation are crucial for improving early diagnosis, risk stratification, and …

Epithelial cell adhesion molecule: an anchor to isolate clinically relevant circulating tumor cells

In the last few decades, the epithelial cell adhesion molecule (EpCAM) has received
increased attention as the main membrane marker used in many enrichment technologies to …

Nanostructured substrates for detection and characterization of circulating rare cells: from materials research to clinical applications

J Dong, JF Chen, M Smalley, M Zhao, Z Ke… - Advanced …, 2020 - Wiley Online Library
Circulating rare cells in the blood are of great significance for both materials research and
clinical applications. For example, circulating tumor cells (CTCs) have been demonstrated …

The role of circulating tumor cells in the metastatic cascade: biology, technical challenges, and clinical relevance

H Dianat-Moghadam, M Azizi, Z Eslami-S… - Cancers, 2020 - mdpi.com
Metastases and cancer recurrence are the main causes of cancer death. Circulating Tumor
Cells (CTCs) and disseminated tumor cells are the drivers of cancer cell dissemination. The …

Circulating tumour cells: a broad perspective

V Akpe, TH Kim, CL Brown… - Journal of the Royal …, 2020 - royalsocietypublishing.org
Circulating tumour cells (CTCs) have recently been identified as valuable biomarkers for
diagnostic and prognostic evaluations, as well for monitoring therapeutic responses to …

3D printed microfluidic devices for circulating tumor cells (CTCs) isolation

J Chen, CY Liu, X Wang, E Sweet, N Liu… - Biosensors and …, 2020 - Elsevier
Isolation of circulating tumor cells (CTCs) from blood samples has important prognostic and
therapeutic implications for cancer treatments, but the process is very challenging due to the …

Advanced diagnostic aids for oral cancer

MG Madhura, RS Rao, S Patil, HN Fageeh, A Alhazmi… - Disease-a-month, 2020 - Elsevier
Oral cancer, a universal malady, has become a stumbling block over the years due to its
significant morbidity and mortality rates. The greater morbidity associated with this deadly …

Treating tumors with minimally invasive therapy: A review

P Wang, S Sun, H Ma, S Sun, D Zhao, S Wang… - Materials Science and …, 2020 - Elsevier
With high level of morbidity and mortality, tumor is one of the deadliest diseases worldwide.
Aiming to tackle tumor, researchers have developed a lot of strategies. Among these …

A novel microfluidic device integrating focus-separation speed reduction design and trap arrays for high-throughput capture of circulating tumor cells

C Lu, J Xu, J Han, X Li, N Xue, J Li, W Wu, X Sun… - Lab on a Chip, 2020 - pubs.rsc.org
Isolation and analysis of circulating tumor cells (CTCs) from peripheral blood provides a
potential way to detect and characterize cancer. Existing technologies to separate or capture …

The Combination of immunomagnetic bead-based cell isolation and optically induced dielectrophoresis (ODEP)-based microfluidic device for the negative selection …

PY Chu, CH Hsieh, MH Wu - Frontiers in bioengineering and …, 2020 - frontiersin.org
Negative selection-based circulating tumor cell (CTC) isolation is able to harvest viable,
label-free, and clinically meaningful CTCs from the cancer patients' blood. Nevertheless, its …