Nanocurcumin: A promising candidate for therapeutic applications

A Karthikeyan, N Senthil, T Min - Frontiers in Pharmacology, 2020 - frontiersin.org
Curcuma longa is an important medicinal plant and a spice in Asia. Curcumin
(diferuloylmethane) is a hydrophobic bioactive ingredient found in a rhizome of the C. longa …

Therapeutic effects of kaempferol affecting autophagy and endoplasmic reticulum stress

M Ashrafizadeh, S Tavakol, Z Ahmadi… - Phytotherapy …, 2020 - Wiley Online Library
Regulated cell death (RCD) guarantees to preserve organismal homeostasis. Apoptosis and
autophagy are two major arms of RCD, while endoplasmic reticulum (ER) as a crucial …

Bioactive anti-inflammatory, antibacterial, antioxidative silicon-based nanofibrous dressing enables cutaneous tumor photothermo-chemo therapy and infection …

Y Xi, J Ge, M Wang, M Chen, W Niu, W Cheng, Y Xue… - Acs Nano, 2020 - ACS Publications
Traditional skin tumor surgery and chronic bacterial-infection-induced wound healing/skin
regeneration is still a challenge. The ideal strategy should eliminate the tumor, enhance …

Self-assembled herbal medicine encapsulated by an oxidation-sensitive supramolecular hydrogel for chronic wound treatment

W Zhao, X Zhang, R Zhang, K Zhang… - ACS Applied Materials …, 2020 - ACS Publications
Inflammation has been assumed to affect the pathology of wound healing and is associated
with many nonhealing chronic wounds. Naturally derived herbal medicines with anti …

Sensing the scent of death: modulation of microRNAs by curcumin in gastrointestinal cancers

M Ashrafizadeh, A Zarrabi, M Hashemipour… - Pharmacological …, 2020 - Elsevier
Gastrointestinal (GI) cancers with a high incidence rate and adverse complications are
related to severe morbidity and mortality around the world. MicroRNAs (miRs) are potential …

The role of curcumin/curcuminoids during gastric cancer chemotherapy: a systematic review of non-clinical study

M Najafi, K Mortezaee, M Rahimifard, B Farhood… - Life sciences, 2020 - Elsevier
Aims Chemotherapy is an effective therapeutic modality which is commonly used for battling
various cancers. However, several side effects induced by chemotherapeutic drugs would …

Toward regulatory effects of curcumin on transforming growth factor-beta across different diseases: a review

M Ashrafizadeh, A Zarrabi, K Hushmandi… - Frontiers in …, 2020 - frontiersin.org
Immune response, proliferation, migration and angiogenesis are juts a few of cellular events
that are regulated by transforming growth factor-β (TGF-β) in cells. A number of studies have …

Curcumin's beneficial effects on neuroblastoma: mechanisms, challenges, and potential solutions

K Zhai, A Brockmüller, P Kubatka, M Shakibaei… - Biomolecules, 2020 - mdpi.com
Curcumin, a natural polyphenolic compound derived from the South Asian turmeric plant
(Curcuma longa), has well-characterized antioxidant, anti-inflammatory, anti-protein …

Application of functional biocompatible nanomaterials to improve curcumin bioavailability

Z Li, M Shi, N Li, R Xu - Frontiers in Chemistry, 2020 - frontiersin.org
Curcumin is a lipophilic natural product extracted from turmeric and commonly used as a
dietary spice. Being multi-functional, curcumin has been proposed in the prevention and …

Curcumin: A therapeutic potential in ageing-related disorders

A Vaiserman, A Koliada, A Zayachkivska, O Lushchak - PharmaNutrition, 2020 - Elsevier
Background Chronic oxidative stress and inflammation are known to be among the leading
causes of ageing. Therefore, dietary supplementation with bioactive phytochemicals having …