Astrocytes play important roles in numerous central nervous system disorders including
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …

Iron is a key nutrient for normal central nervous system (CNS) development and function;
thus, iron deficiency as well as iron excess may result in harmful effects in the CNS …

Over the last decade knowledge of the role of astrocytes in central nervous system (CNS)
neuroinflammatory diseases has changed dramatically. Rather than playing a merely …

Amyloid‐β (Aβ) dysmetabolism is tightly associated with pathological processes in
Alzheimer's disease (AD). Currently, it is thought that, in addition to Aβ fibrils that give rise to …

Progesterone and testosterone, beyond their roles as sex hormones, are neuroactive
steroids, playing crucial regulatory functions within the nervous system. Among these …

Tuberous sclerosis complex (TSC) represents the prototypic monogenic disorder of the
mammalian target of rapamycin (mTOR) pathway dysregulation. It provides the rational …

The brain's endogenous capacity to restore damaged myelin deteriorates during the course
of demyelinating disorders. Currently, no treatment options are available to establish …

Glioblastoma (GBM) develops from adult brain white matter and is the most common and
lethal primary brain tumor, characterized by rapid growth and invasion. GBM tumors …

Introduction Multiple sclerosis (MS) is a demyelinating autoimmune disease of the central
nervous system (CNS), in which astrocytes play an important role as CNS immune cells …

Introducción La esclerosis múltiple (EM) es una enfermedad autoinmune desmielinizante
del sistema nervioso central (SNC) en la que los astrocitos tienen una participación …