Predicting drug resistance using deep mutational scanning

G Pines, RG Fankhauser, CA Eckert - Molecules, 2020 - mdpi.com
Drug resistance is a major healthcare challenge, resulting in a continuous need to develop
new inhibitors. The development of these inhibitors requires an understanding of the …

The apicoplast as a target for new interventions against malaria: further investigations towards a whole organism vaccination

L Boger - 2020 - ub01.uni-tuebingen.de
Despite successful efforts to decrease suffering from malaria, the impact on global health still
is enormous. Prevention is a key element in the fight against this parasitic disease. Malaria …

Dynamic flexibility of protein prenyltransferase activities

Q Chevalier - 2020 - theses.hal.science
The protein prenylation is a key post-translational modification for the development,
signaling and environmental adaptation of eukaryotic cells. Although many active and …